Results 111 to 120 of about 443,134 (353)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Non-linear simulations of combustion instabilities with a quasi-1D Navier-Stokes code
, 2010 As lean premixed combustion systems are more susceptible to combustion instabilities than non-premixed systems, there is an increasing demand for improved numerical design tools that can predict the occurrence of combustion instabilities with high ...
Allam +29 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
MathematicsThis paper investigates the dispersion of atmospheric pollutants in urban environments using a fractional-order convection–diffusion-reaction model with dynamic line sources associated with vehicle traffic.
Muratkan Madiyarov +4 more
doaj +1 more source
Effect of Inhomogeneous Mixing on Chemical Reaction in a Taylor Vortex Flow Reactor.
JOURNAL OF CHEMICAL ENGINEERING OF JAPAN, 2002 Effect of inhomogeneous mixing on chemical reactions in a Taylor vortex flow reactor was experimentally investigated by using a second-order reaction system. The flow-visualization experiment by a laser induced fluorescence method was also carried out to observe the cross-sectional view of mixing behavior in the inside of Taylor vortex cells.
Naoto Ohmura +3 more
openaire +1 more source
Nucleosynthesis in Baryon-Rich Outflows Associated With Gamma-Ray Bursts
, 2003 Robust generation of gamma-ray bursts (GRBs) implies the formation of outflows with very low baryon loads and highly relativistic velocities, but more baryon-rich, slower outflows are also likely to occur in most GRB central engine scenarios, either as ``
Bisnovatyi-Kogan G. S. +9 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Advances in State-to-State Reaction Rate Coefficients for High-Temperature Nonequilibrium Flows
气体物理During cruise and re-entry phases, hypersonic vehicles generate high post-shock temperatures reaching several thousand to tens of thousands of Kelvin, inducing complex physicochemical processes that critically affect gas radiation and aerodynamic heating.
Qizhen HONG +11 more
doaj +1 more source
Thin front propagation in random shear flows
, 2005 Front propagation in time dependent laminar flows is investigated in the limit of very fast reaction and very thin fronts, i.e. the so-called geometrical optics limit.
A. N. Kolmogorov +9 more
core +1 more source