Results 231 to 240 of about 14,626,809 (402)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Analysis of Multi-Zone Reaction Mechanisms in BOF Steelmaking and Comprehensive Simulation. [PDF]

Materials (Basel)
Xin Z, Liu Q, Zhang J, Lin W.
europepmc   +1 more source

Degradation of a New Herbicide Florpyrauxifen-Benzyl in Water: Kinetics, Various Influencing Factors and Its Reaction Mechanisms. [PDF]

Int J Mol Sci, 2023
Zhou R, Dong Z, Wang L, Zhou W, Zhao W, Wu T, Chang H, Lin W, Li B.   +8 more
europepmc   +1 more source

Kinetics and Mechanism of Oxygen Reduction Reaction at Carbon-Supported Palladium Catalysts Using Rotating Ring Disk Electrode [PDF]

, 2012
Lisandra Arroyo‐Ramírez, Raphael G. Raptis, Carlos R. Cabrera   +2 more
openalex   +1 more source

The Ir–OOOO–Ir transition state and the mechanism of the oxygen evolution reaction on IrO ₂ (110)

, 2022
Tobias Binninger, Marie‐Liesse Doublet
openalex   +2 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Aqueous-Phase Reaction Mechanisms of Small α-Dicarbonyls in the Presence of Phthalate Esters. [PDF]

Toxics
Li W, Shi Q, Wang J, Ma R, Gao Y, Ji Y.
europepmc   +1 more source

EPR Spectroscopy Provides New Insights into Complex Biological Reaction Mechanisms. [PDF]

J Phys Chem B, 2022
Hofmann L, Ruthstein S.
europepmc   +1 more source

Multiscale Simulations of SARS-CoV-2 3CL Protease Inhibition with Aldehyde Derivatives. Role of Protein and Inhibitor Conformational Changes in the Reaction Mechanism

, 2021
Carlos A. Ramos‐Guzmán, J. Javier Ruiz‐Pernía, Iñaki Tuñón   +2 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source