Results 91 to 100 of about 18,725,282 (303)

Reaction time and sensorimotor integration in schizophrenia

open access: yesDialogues in Clinical Neuroscience & Mental Health, 2018
The deficit of information processing speed reflected in the increase of reaction time (RT) in sensorimotor speeded decision-making tasks is among the most replicated findings in Schizophrenia.
Nikolaos Smyrnis
doaj   +1 more source

Measuring sexual interest using a pictorial modified Stroop task, a pictorial Implicit Association Test, and a Choice Reaction Time task [PDF]

open access: yes, 2013
Tasks that can successfully measure sexual interest have utility in forensic settings. Prior to use with problematic sexual interest however, work is needed in validating such tasks.
Gormley, Michael, Ó Ciardha, Caoilte
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Threshold units: A correct metric for reaction time? [PDF]

open access: yes, 2007
Purpose:To compare reaction time (RT) to rod incremental and decremental stimuli expressed in physical contrast units or psychophysical threshold units.Methods:Rod contrast detection thresholds and suprathreshold RTs were measured for Rapid-On and Rapid ...
Cao, Dingcai   +2 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Influence of practice on visual reaction time

open access: yesJournal of Mahatma Gandhi Institute of Medical Sciences, 2014
Background: The present study was aimed to see the effect of practice on visual information processing speed. Reaction time is one of the important physiological parameters, which gives information how fast and quickly person responses.
Tejas P Ghuntla   +3 more
doaj   +1 more source

Ring closing reaction in diarylethene captured by femtosecond electron crystallography [PDF]

open access: yes, 2013
The photoinduced ring closing reaction in diarylethene, which serves as a modelsystem for understanding reactive crossings through conical intersections, was directly observed with atomic resolution using femtosecond electron diffraction.
Liu, Lai Chung   +15 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The reaction-time technique in brand attributes testing

open access: yes, 2004
From the angle of consumer behavior, brand attributes is the associations related with the brand name stored in consumer’s long-term memory as a network.
W. Yong, M. C. Ma, C. L. Fan, L. Lei
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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