Results 91 to 100 of about 2,953,194 (309)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Reactive and reactive-diffusive time scales in stiff reaction-diffusion systems [PDF]

open access: yes, 2005
Two different sets of time scales arising in stiff systems of reaction-diffusion PDEs are examined; the first due to the reaction term alone and the second due to the interaction of the reaction and diffusion terms, The fastest time scales of each set ...
Creta, F   +7 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Reliability of computerized eye-tracking reaction time tests in non-athletes, athletes, and individuals with traumatic brain injury [PDF]

open access: yes, 2018
Background: Eye tracking technologies and methodologies have advanced significantly in recent years. Specifically, the use of eye tracking to quantitatively measure oculomotor and psychophysiological constructs is gaining momentum. Reaction time has been
Lange, Belinda   +4 more
core  

Reaction time. [PDF]

open access: yesPsychological Bulletin, 1910
n ...
openaire   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Reaction-Time Measurements: Their Use and Limitations in Diagnosis [PDF]

open access: yes, 1933
From the early stages of modern experimental psychology-reaction-time experiments have been used in the endeavor to study different psychological processes such as the effect of distracting stimuli on attention, the influence of drugs and alcohol, the ...
Gilbert Stillman MacVaugh (16742760)
core  

Time-Resolved Resonance Raman Study of Triplet Arylnitrenes and Their Dimerization Reaction [PDF]

open access: yes, 2016
Time-resolved resonance Raman spectra for triplet 4-methoxyphenyl nitrene and 4-ethoxyphenyl nitrene and their dimerization reaction to form azo dimer products in acetonitrile solution on the nanosecond time scale are reported.
Pik Ying Chan (2469091)   +4 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Probing state-to-state reaction dynamics using H-atom Rydberg tagging time-of-flight spectroscopy [PDF]

open access: yes, 2011
Probing state-to-state reaction dynamics using H-atom Rydberg tagging time-of-flight spectroscopyIn the last decade or so, the H-atom Rydberg tagging time-of-flight (HRTOF) technique has made a significant impact in the study of state-to-state reaction ...
Yang, Xueming, 杨学明
core   +1 more source

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