Results 101 to 110 of about 18,725,282 (303)

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Study on the manifestation of reaction speed at young athletes (basketball vs football players)

open access: yesAnnals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement
The present study tries to make a comparison between the specific performances of the reaction speed between 2 groups of subjects, basketball and football athletes – Under 10 category, boys.
LAKOTOS Ilie Ionuț   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Effect of Mobile Use on Reaction Time [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2010
The use of cellular phones has skyrocketed in recent years, with more than 118 million subscribers in the United States as of July 1, 2001. Recent estimates suggest that cell phone users spend 60% of their cell phone time while driving.
Chinmay Shah, P A Gokhale, H.B. Mehta
doaj  

The reaction time to touch [PDF]

open access: yesThe Journal of Physiology, 1954
P P, LELE, D C, SINCLAIR, G, WEDDELL
openaire   +2 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Under the Clouds of War

open access: yes, 1972
Consists of film clips of World War II events, including Mussolini\u27s invasion of Ethiopia and Hitler\u27s march into Austria.
Time-Life Video
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Persistent developmental stuttering as a cortical-subcortical dysfunction: evidence from muscle activation Gagueira persistente do desenvolvimento como disfunção córtico-subcortical: evidências pela ativação muscular

open access: yesArquivos de Neuro-Psiquiatria, 2008
BACKGROUND: One contemporary view of stuttering posits that speech disfluencies arise from anomalous speech motor control. PURPOSE: To verify the rest muscle tension and speech reaction time of fluent and stuttering adults.
Claudia Regina Furquim de Andrade   +3 more
doaj   +1 more source

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