Results 81 to 90 of about 5,905,665 (347)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The effect of juggling on the proprioceptive and attentional abilities among older women

open access: yesFrontiers in Public Health
BackgroundAge-related changes in attentional abilities can lead to a decline in body segment awareness in space. However, studies have reported that physical activity can improve proprioception among older adults, although proven activities with this ...
Jakub Malik   +3 more
doaj   +1 more source

Localization-delocalization transition of a reaction-diffusion front near a semipermeable wall

open access: yes, 1997
The A+B --> C reaction-diffusion process is studied in a system where the reagents are separated by a semipermeable wall. We use reaction-diffusion equations to describe the process and to derive a scaling description for the long-time behavior of the ...
A. Büki   +31 more
core   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Time-fractional equations with reaction terms: fundamental solutions and asymptotics

open access: yes, 2019
We analyze the fundamental solution of a time-fractional problem, establishing existence and uniqueness in an appropriate functional space. We also focus on the one-dimensional spatial setting in the case in which the time-fractional exponent is equal ...
Dipierro, Serena   +3 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

The relationship between attentional control and injury-related biomechanics in young female volleyball players

open access: yesFrontiers in Physiology
BackgroundAdolescent athletes, particularly in team sports, exhibit high risk of non-contact injuries due to the open environment and risk-associated movements.
Ivana Hanzlíková   +5 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Analysis of goal, feedback and rewards on sustained attention via machine learning

open access: yesFrontiers in Behavioral Neuroscience
IntroductionSustaining attention is a notoriously difficult task as shown in a recent experiment where reaction times (RTs) and pupillometry data were recorded from 350 subjects in a 30-min vigilance task.
Nethali Fernando   +5 more
doaj   +1 more source

Time--space white noise eliminates global solutions in reaction diffusion equations

open access: yes, 2008
We prove that perturbing the reaction--diffusion equation $u_t=u_{xx} + (u_+)^p$ ($p>1$), with time--space white noise produces that solutions explodes with probability one for every initial datum, opposite to the deterministic model where a positive ...
Bandle   +19 more
core   +1 more source

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