Results 171 to 180 of about 26,803 (327)

Oxime@Zirconium-Metal-Organic Framework Hybrid Material as a Potential Antidote for Organophosphate Poisoning. [PDF]

Inorg Chem, 2023
González L, Martín-Romera JD, Sánchez-Sánchez P, Navarro JAR, Barea E, Maldonado CR, Carmona FJ.   +6 more
europepmc   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Hepatitis B and C Virus Reactivation Patterns in a Romanian Cohort of Patients with Chronic Lymphoproliferative Disorders [PDF]

, 2019
Violeta Molagic, Raluca Mihăilescu, Cătălin Tilişcan, Cristina Popescu, Ana Maria Vlădăreanu, Remulus Catană, Mihaela Rădulescu, Victoria Aramă, Ștefan Sorin Aramă   +8 more
openalex   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

HIV-1 latency reversal agent boosting is not limited by opioid use

JCI Insight
Opioid use may affect the HIV-1 reservoir and its reversal from latency. We studied 47 virally suppressed people with HIV (PWH) and observed that lower concentration of HIV-1 latency reversal agents (LRAs), used with small molecules that did not reverse ...
Tyler Lilie, Jennifer Bouzy, Archana Asundi, Jessica Taylor, Samantha Roche, Alex Olson, Kendyll Coxen, Heather Corry, Hannah Jordan, Kiera Clayton, Nina Lin, Athe Tsibris   +11 more
doaj   +1 more source

Progress in Antidotes (Acetylcholinesterase Reactivators) Against Organophosphorus Pesticides [PDF]

, 2011
Anna Horova, Daniel Jun, Jana Zdarova-Karasova, Kamil Kuca, Kamil Musilek, Miroslav Pohanka, Ondrej Holas   +6 more
core   +2 more sources

Reactive syringofibroadenoma

Indian Journal of Dermatology, Venereology and Leprology, 2020
Piyush, Kumar, Anupam, Das, P C, Das
openaire   +2 more sources

Patient-derived HIV reservoirs can be stably engrafted into NSG mice and reactivated by latency-reversing agents in vivo

, 2017
Adam R. Ward, Enock Charleus, S. Karandish, Erika Benko, Colin Kovacs, Dora Chan, Anahita Ramezani, R. Brad Jones   +7 more
openalex   +1 more source

EBV-reactivation and posttransplant lymphoproliferative disorder treated with rituximab [PDF]

, 2013
Vikas Dua, Satya Prakash Yadav
openalex   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source