Results 221 to 230 of about 26,803 (327)

Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development. [PDF]

open access: yesACS Med Chem Lett
Vu BT   +13 more
europepmc   +1 more source

SIV Evolutionary Dynamics in Cynomolgus Macaques during SIV-Mycobacterium tuberculosis Co-Infection. [PDF]

open access: yesViruses, 2021
Tisthammer KH   +7 more
europepmc   +1 more source

Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu   +11 more
wiley   +1 more source

Synthesis and Evaluation of Halogenated Pralidoximes in Reactivation of Organophosphate-Inhibited Cholinesterases. [PDF]

open access: yesACS Med Chem Lett
Knittelova K   +8 more
europepmc   +1 more source

Hepatitis B Reactivation and Rituximab in the Oncology Practice [PDF]

open access: bronze, 2010
Jeryl Villadolid   +4 more
openalex   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

open access: yesAdvanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge   +9 more
wiley   +1 more source

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