Results 241 to 250 of about 124,194 (317)

scL-2PAM: A Novel Countermeasure That Ameliorates Neuroinflammation and Neuronal Losses in Mice Exposed to an Anticholinesterase Organophosphate. [PDF]

Int J Mol Sci
Moghe M, Kim SS, Guan M, Rait A, Pirollo KF, Harford JB, Chang EH.   +6 more
europepmc   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Ferroptosis in AML: nanoparticles, biomarkers, and immune rewiring for therapeutic breakthroughs. [PDF]

Discov Oncol
Tavakoli F, Araskhan MA, Karimpour F, Soleimani Samarkhazan H, Hasheminasab H, Roshandel E, Vazifeh Shiran N, Dehghanifard A, Mohammadi MH.   +8 more
europepmc   +1 more source

Targeting p53 in anticancer therapy: Searching for new small molecule activators. [PDF]

, 2018
Beatriz Sampaio da Silva
core  

Multifunctional hyaluronic acid hydrogel integrating exosome‐encapsulating gelatin microspheres accelerates skeletal muscle regeneration via TGF‐β1 activation and enhanced myogenic cell viability

BMEMat, EarlyView.
Schematic illustration of preparation of injectable H/G@Co@miR‐206 hydrogel for efficient skeletal muscle regeneration in cardiotoxin‐induced skeletal muscle injury SD rat model. Abstract The effective treatment of acute skeletal muscle injuries remains challenging, necessitating therapeutic strategies that concurrently reestablish vascular perfusion ...
Zhengzhe Han, Zongyue Li, Ang Li, Zheng Jiang, Saiyu Shi, Zhipeng Wang, Jishizhan Chen, Yun Qian, Yuanyang Gu, Xianyou Zheng   +9 more
wiley   +1 more source

A Pralidoxime Nanocomplex Formulation Targeting Transferrin Receptors for Reactivation of Brain Acetylcholinesterase After Exposure of Mice to an Anticholinesterase Organophosphate. [PDF]

Int J Nanomedicine
Pirollo KF, Moghe M, Guan M, Rait AS, Wang A, Kim SS, Chang EH, Harford JB.   +7 more
europepmc   +1 more source

Integrated spherical nucleic acid nanoreactor mobilizes targeted PD‐L1 proteolysis and cuproptosis for robust breast cancer immunotherapy

BMEMat, EarlyView.
This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li, Honglin Huang, Qianyi Zeng, Li Zeng, Ziman Yang, Jinyang Shen, Shun Li, Hong Yang, Yiyao Liu, Chunhui Wu   +9 more
wiley   +1 more source

Advancements in bioscavenger mediated detoxification of organophosphorus poisoning. [PDF]

Toxicol Res (Camb)
Li H, Lu C, Liu Z, Xiang F, Liu B, Wang H, Chang J, Pan L, Chen Y, Chen J.   +9 more
europepmc   +1 more source

Screening of efficient salicylaldoxime reactivators for DFP and paraoxon-inhibited acetylcholinesterase. [PDF]

RSC Med Chem
Wei Z, Zhang D, Liu X, Nie H, Ouyang Q, Zhang X, Zheng Z.   +6 more
europepmc   +1 more source

Molecular targets and therapies associated with poor prognosis of triple‑negative breast cancer (Review). [PDF]

Int J Oncol
Kim ES.
europepmc   +1 more source