Results 61 to 70 of about 269,423 (199)

Role of cellular senescence and NOX4-mediated oxidative stress in systemic sclerosis pathogenesis. [PDF]

open access: yes, 2015
Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by progressive fibrosis of skin and numerous internal organs and a severe fibroproliferative vasculopathy resulting frequently in severe disability and high mortality.
A Diazdeleon   +130 more
core   +2 more sources

Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia [PDF]

open access: yes, 2004
We previously demonstrated prolonged, profound CD4+ T-lymphopenia in rheumatoid arthritis (RA) patients following lymphocyte-depleting therapy. Poor reconstitution could result either from reduced de novo T-cell production through the thymus or from poor
Bingham, S.J.   +26 more
core   +2 more sources

Cohort profile of a US military population for evaluating pre-disease and disease serological biomarkers in rheumatoid and reactive arthritis: Rationale, organization, design, and baseline characteristics

open access: yesContemporary Clinical Trials Communications, 2020
Purpose: The etiology of several autoimmune disorders, including rheumatoid arthritis, remains unknown. While there are clear phases of disease progression, the mechanisms of transition between these phases are poorly understood.
Chad K. Porter   +10 more
doaj   +1 more source

TCD4pos lymphocytosis in rheumatoid and psoriatic arthritis patients following TNFα blocking agents [PDF]

open access: yes, 2017
BACKGROUND: Lymphocyte expansion and true lymphocytosis are commonly observed in the everyday clinical practice. The meaning of such phenomenon is often poorly understood so that discrimination between benign and malignant lymphocytosis remains ...
Amodeo, Rachele   +11 more
core   +1 more source

Osteomyelitis infection disguised as Reiter's syndrome in a child: A case report

open access: yesClinical Case Reports, 2021
Reiter's syndrome (reactive arthritis) should always prompt a thorough clinical investigation of a potentially more serious disease condition in every pediatric patient and adults. It should always be regarded as a warning sign and not a disease. This is
Nnennaya U. Opara
doaj   +1 more source

Seronegative spondyloarthropathies : a review : part II: genetics and pathogenesis [PDF]

open access: yes, 1993
In none of the spondyloarthropathies is the pathogenesis well understood. Much of the investigation into the aetio-pathogenesis of these diseases has focused on the association with HLA-B27 and the known triggering potential of certain infectious agents.
Borg, Andrew A.   +2 more
core  

HETEROGENEITY OF POLYCLONAL IMMUNOGLOBULINS NUCLEASE ACTIVITY IN RHEUMATOID AND REACTIVE ARTHRITIS

open access: yesМедицинская иммунология, 2017
Catalytic properties of immunoglobulins are widely studied within recent years. It was found that nuclease activity of immunoglobulins is increased in systemic autoimmune diseases.
M. V. Volkova   +3 more
doaj   +1 more source

Chronic seronegative spondyloarthropathy following acute Mycoplasma pneumoniae infection in a human leukocyte antigen B27-positive patient: a case report

open access: yesJournal of Medical Case Reports, 2020
Background We report a case of a 30-year-old patient who presented with acute Mycoplasma pneumoniae infection that was complicated by reactive arthritis and asymmetric proximal myopathy and progressed to chronic spondyloarthropathy.
Georgios Pilianidis   +4 more
doaj   +1 more source

Microbiota and chronic inflammatory arthritis. an interwoven link [PDF]

open access: yes, 2016
Background: Only recently, the scientific community gained insights on the importance of the intestinal resident flora for the host's health and disease.
D'Amelio, Raffaele   +3 more
core   +2 more sources

Neopterin as a Surrogate Marker for Coronary Artery Disease in Rheumatoid Arthritis

open access: yesمجلة كلية الطب
Background: Rheumatoid arthritis is an inflammatory illness. A complication of Rheumatoid arthritis is mainly linked to the risk of cardiovascular disease.
Maryam K. Khaery, Rana A. Hamdi
doaj   +1 more source

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