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Interactions between nitric oxide, oxygen, reactive oxygen species and reactive nitrogen species
Biochemical Society Transactions, 2006ROS (reactive oxygen species) and RNS (reactive nitrogen species) are central to the innate immunity that protects us from infection, but also contribute to degenerative diseases and possibly aging. However, ROS and RNS are increasingly recognized to contribute to physiological signalling. This review briefly describes the main interactions between ROS
G C, Brown, V, Borutaite
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Reactive Oxygen Species and Reactive Nitrogen Species in Epigenetic Modifications
2014For the normal homeostasis of a cell, there must be a balance between radical oxygen species/radical nitrogen species (ROS/RNS) production and the neutralization of these species by antioxidant scavenging. In times of stress, this balance is not maintained, and the result is oxidative stress.
Baird, Anne-Marie +2 more
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Electrochemical generation of reactive nitrogen species
Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 1990Abstract The anodic behavior of N,N-dialkylanilines having various kinds of electron-withdrawing groups at their α-positions was studied comparatively in methanol. These anilines underwent α-methoxylation and/or cleavage of a carbon-nitrogen bond depending on the kind of N-alkyl and electron-withdrawing groups.
Toshio Fuchigami +2 more
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THE REACTIVE SPECIES IN ACTIVE NITROGEN
Canadian Journal of Chemistry, 1962A study has been made of the discrepancy between the N-atom content of active nitrogen as inferred from the maximum HCN production from the reaction of many hydrocarbons, and that indicated by the extent of NO destruction. The HCN production from several hydrocarbons was similar at high reaction temperatures in a spherical reaction vessel, and was ...
A. N. Wright +2 more
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[Reactive oxygen and nitrogen species].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2012Reactive oxygen and nitrogen species (ROS and RNS respectively) play an important role in the proper functioning of many cellular processes. Generation of reactive oxygen species is an integral part of aerobic metabolism of cells. Their overproduction and subsequent oxidative stress occurs during pathogenesis of many diseases.
Mateusz, Ługowski +3 more
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Aging and the Role of Reactive Nitrogen Species
Annals of the New York Academy of Sciences, 2002AbstractThe role of reactive oxygen species and its effects on aging has received considerable attention in the past 47 years since Dr. Denham Harman first proposed the “free radical theory of aging.” Though not completely understood due to the incalculable number of pathways involved, the number of manuscripts that facilitate the understanding of the ...
Barry, Drew, Christiaan, Leeuwenburgh
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Transthyretin Aggregates Induce Production of Reactive Nitrogen Species
Neurodegenerative Diseases, 2012<b><i>Background and Objective:</i></b> Misfolded and aggregated transthyretins (agTTR) contribute to neurodegenerative amyloid diseases such as familial amyloid polyneuropathy and senile systemic amyloidosis. The neurotoxicity mechanisms of agTTR, however, are not well understood. In the current study, the possible contribution
Vai-Hong, Fong, Amandio, Vieira
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Imaging of Intracellular Reactive Nitrogen Species and Reactive Sulfur Species
2020This chapter summarizes representative small-molecule fluorescent probes for reactive nitrogen species and reactive sulfur species in living cells. The design and response mechanisms of the probes are described in detail. Probes that have not been applied in living cell analysis are not included.
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Reactive nitrogen and oxygen species in airway inflammation
European Journal of Pharmacology, 2001The free radical nitric oxide (NO) is an important mediator of many biological processes. Interestingly, the molecule appears to be a two-edged sword. Apart from NO having a function as a paracrine messenger, NO-derived oxidants are important weapons against invading pathogens. The role of NO in the airways is similarly ambiguous. Besides the task as a
Folkerts, G. +3 more
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Reactive oxygen species, reactive nitrogen species and redox signalling
2016This chapter explains our current understanding of how reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated and perceived, and how they propagate their messages. It argues that the main components involved here include those used in phosphorylation and cyclic nucleotides.
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