Results 81 to 90 of about 5,566,634 (283)

Nitrated Nucleotides: New Players in Signaling Pathways of Reactive Nitrogen and Oxygen Species in Plants

open access: yesFrontiers in Plant Science, 2020
Nitration of diverse biomolecules, including proteins, lipids and nucleic acid, by reactive nitrogen species represents one of the key mechanisms mediating nitric oxide (NO) biological activity across all types of organisms.
Marek Petřivalský, Lenka Luhová
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Dissolved organic carbon and nitrogen leaching from Scots pine, Norway spruce and silver birch stands in southern Sweden [PDF]

open access: yes, 2011
The effects of three common tree species – Scots pine, Norway spruce and silver birch – on leaching of dissolved organic carbon and dissolved nitrogen were studied in an experimental forest with podzolised soils in southern Sweden. We analyzed soil water
Kleja, Dan Berggren   +3 more
core   +2 more sources

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Antioxidant therapy for hypertension; a mini-review on the recent findings [PDF]

open access: yesJournal of Nephropharmacology
Oxidative stress is a key mechanism underlying hypertension. Therefore, antioxidant therapy is an attractive concept for hypertension. Antioxidant therapy has been shown to have a significant impact on blood pressure reduction in various studies.
Samira Mehrabi Pari   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

RETRASO, a code for modeling reactive transport in saturated and unsaturated porous media [PDF]

open access: yes, 2004
The code RETRASO (REactive TRAnsport of SOlutes) simulates reactive transport of dissolved and gaseous species in non-isothermal saturated or unsaturated problems.
Saaltink, Maarten   +13 more
core   +1 more source

High‐Resolution Corrosion Fingerprinting of Alloy Libraries via Microdroplet Spectroelectrochemistry

open access: yesAdvanced Engineering Materials, EarlyView.
Ionic‐liquid microdroplet spectroelectrochemistry enables stable, localized electrochemical measurements over extended timescales. By coupling impedance spectroscopy, wetting analysis, finite‐element simulations, and operando Raman spectroscopy, it disentangles geometrical and electrochemical effects, opening new opportunities for rapid corrosion ...
Ekaterina Kurchavova   +3 more
wiley   +1 more source

Oxidative Stress in Renal Health

open access: yesAntioxidants
Oxidative stress is caused by the increase in reactive oxygen species (ROS) and reactive nitrogen species (RNS) inside cells [...]
Ana Cristina Simões e Silva
doaj   +1 more source

Dietary Antioxidant An Indispensible Nutrient

open access: yesJournal of Bahria University Medical and Dental College, 2019
Free radicals prevail as atoms, molecules or unpaired electrons being extremely reactive as well as unstable1. They can lead to chemical reactions alongside different molecules.
Shizma Junejo   +2 more
doaj   +1 more source

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