Results 111 to 120 of about 1,320,983 (289)

Flow Cytometric Detection of Reactive Oxygen Species

Bio-Protocol, 2013
Reactive oxygen species (ROS) are molecules containing hydroxyl radicals or peroxides with unpaired electrons. In healthy aerobic cells, ROS are produced naturally as a byproduct of oxidative phosphorylation, oxidoreductase enzymes, or metal catalyzed ...
Hsin-Yi Chang, Hsuan-Cheng Huang, Tsui-Chin Huang, Pan-Chyr Yang, Yi-Ching Wang, Hsueh-Fen Juan   +5 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Nickel nanowires induced and reactive oxygen species mediated apoptosis in human pancreatic adenocarcinoma cells

International Journal of Nanomedicine, 2011
Md. Zakir Hossain1, Maurice G Kleve21Applied Biosciences (Bionanotechnology Research), Department of Applied Science, 2Molecular Biotechnology and Microscopy Laboratory, Department of Biology, University of Arkansas at Little Rock, Little Rock, Arkansas,
Kleve MG, Hossain MZ
doaj  

Separation of VUV/UV photons and reactive particles in the effluent of a He/O2 atmospheric pressure plasma jet

, 2011
Cold atmospheric pressure plasmas can be used for treatment of living tissues or for inactivation of bacteria or biological macromolecules. The treatment is usually characterized by a combined effect of UV and VUV radiation, reactive species, and ions ...
B Denis, Bibinov N K, Broadwater W T, Cao Z, Cartry G, Dobrynin D, Ehlbeck J, Ellerweg D, F Narberhaus, Goree J, J Benedikt, J E Bandow, J-W Lackmann, Jeong J, Knake N, Kong M G, Morfill G, Robert E, S Schneider, Sambrook J, Waskoenig J   +20 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Cytotoxicity and reactive oxygen species generation from aggregated carbon and carbonaceous nanoparticulate materials

International Journal of Nanomedicine, 2008
Kristine M Garza1, Karla F Soto2, Lawrence E Murr31Department of Biological Sciences, The University of Texas at El Paso, El Paso, TX, USA; 2Lockheed Martin Aeronautics Company, Forth Worth, TX, USA; 3Department of Metallurgical and Materials Engineering,
Kristine M Garza, Karla F Soto, Lawrence E Murr   +2 more
doaj  

Degradation of organic compounds and production of activated species in Dielectric Barrier Discharges and Glidarc reactors

, 2007
Major sterilization mechanisms are related to atoms and radicals, charged parti-cles, excited molecules, ozone, and UV radiation. The ROS (Reactive Oxygen Species) are well known as evildoers. These species are easily created in ambient air and water and
Aubry, Olivier, Cormier, Jean Marie, Khacef, Ahmed   +2 more
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

A modeling of the carbon-nitrogen cycle transport at Igap\'o I Lake - Londrina, Paran\'a, Brazil

, 2010
This work is a contribution to better understand the effect that domestic sewage discharges may cause in a water body, specifically Igap\'o I Lake, in Londrina, Paran\'a, Brazil.
Cirilo, Eliandro Rodrigues, Natti, Paulo Laerte, Pardo, Suellen Ribeiro, Romeiro, Neyva Maria Lopes   +3 more
core   +2 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source