Results 91 to 100 of about 6,193,275 (288)

Reactive Oxygen Species (ROS) and Cancer

Reactive oxygen species (ROS) are chemically reactive oxygen radicals or non-radical derivatives playing key role in various biochemical redox reactions.
Sood, R, Soni, JP, Kumar, J
core   +1 more source

Reactive oxygen species in the pathogenesis of sarcopenia

Free Radical Biology and Medicine
One of the most critical factors impacting healthspan in the elderly is the loss of muscle mass and function, clinically referred to as sarcopenia. Muscle atrophy and weakness lead to loss of mobility, increased risk of injury, metabolic changes and loss of independence. Thus, defining the underlying mechanisms of sarcopenia is imperative to enable the
Hongyang Xu, Jacob L. Brown, Shylesh Bhaskaran, Holly Van Remmen   +3 more
openaire   +2 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

The role of reactive oxygen species in the pathogenesis and treatment of endometrial cancer

Frontiers in Medicine
Reactive oxygen species (ROS) play dual roles in the pathophysiology of endometrial cancer (EC). Oxidative stress induced by ROS can promote the survival and proliferation of cancer cells, whereas excessive accumulation of ROS can lead to various forms ...
Jeongmin Lee, Seung Geun Yeo, Seung Geun Yeo, Seung Geun Yeo, Seung Geun Yeo, Jae Min Lee, Sung Soo Kim, Sung Soo Kim, You Jeong Jeong, Tong In Oh, Dong Choon Park   +10 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Plasmon-Assisted Production of Reactive Oxygen Species by Single Gold Nanorods

, 2015
International audienceThe generation of reactive oxygen species by gold nanorods under ultrashort-pulsed irradiation is investigated at the single-nanoparticle level.
Labouret, Timothée, P, Audibert, Jean-Frédéric, Palpant, Bruno, B. Pansu, Robert   +3 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Elicitor effects on reactive oxygen species in liquid cultures of Penicillium chrysogenum

, 2004
Activity of reactive oxygen species (ROS) was investigated in liquid cultures of Penicillium chrysogenum P2 supplemented with carbohydrates. Oligosaccharides lowered the ROS activity in all samples. The greatest effect occurred when oligosaccharides were
Keshavarz, T., Bucke, C., Radman, R.
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Polyphenols of Camellia sinenesis decrease mortality, hepatic injury and generation of cytokines and reactive oxygen and nitrogen species after hemorrhage/resuscitation in rats [PDF]

, 2010
Background: Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are produced during hemorrhagic shock and resuscitation (H/R), which may contribute to multiple organ failure.
Zhong, Zhi, Lehnert, Mark, Schoonhoven, Robert, Marzi, Ingo, Zhi Zhong, Lind, Henrik, Lemasters, John J., Schoonhoven Robert, Lemasters John J, Lehnert Mark, Ingo Marzi, Marzi Ingo, Henrik Lind, Robert Schoonhoven, Zhong Zhi, Lind Henrik, Mark Lehnert, John J Lemasters   +17 more
core   +2 more sources