Results 81 to 90 of about 862,038 (305)

Reactive nitrogen and oxygen species in anticoagulated blood of healthy sheep [PDF]

open access: yes, 2013
Background : Little or no study has been done to compare the indices of ‘nitrosative’ and ‘oxidative’ stresses, especially in terms of correlation and the possible differential effects of the chelating agents.
Nwose, Ezekiel Uba   +2 more
core   +1 more source

Assessing the efficiency of reactive oxygen species colorimetric sensors for use in environmentally & biologically relevant samples [PDF]

open access: yes, 2020
Neal, Sharon L.A longstanding interest in reactive oxygen species (ROS) stems from their role in many environmental, biological, clinical, and industrial processes.
Herman, Johanna L.
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Disease Progression Mediated by Egr-1 Associated Signaling in Response to Oxidative Stress [PDF]

open access: yes, 2012
When cellular reducing enzymes fail to shield the cell from increased amounts of reactive oxygen species (ROS), oxidative stress arises. The redox state is misbalanced, DNA and proteins are damaged and cellular transcription networks are activated.
Deindl, Elisabeth   +3 more
core   +1 more source

Reactive oxygen species and sperm cells

open access: yesReproductive Biology and Endocrinology, 2004
There is a dynamic interplay between pro- and anti-oxidant substances in human ejaculate. Excessive reactive oxygen species (ROS) generation can overwhelm protective mechanism and initiate changes in lipid and/or protein layers of sperm plasma membranes.
Kurpisz Maciej, Sanocka Dorota
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Potential role of NADPH-oxidase in early steps of lead-induced oxidative burst in Vicia faba roots [PDF]

open access: yes, 2008
The mechanism of oxidative burst induced by lead in Vicia faba excised roots was investigated by luminol-dependent chemiluminescence. Results showed that lead triggered a rapid and dose-dependent increase in chemiluminescence production.
Perchet, Geoffrey-Thibault   +7 more
core   +1 more source

Mitochondrial complex II and reactive oxygen species in disease and therapy [PDF]

open access: yes, 2020
Increasing evidence points to the respiratory Complex II (CII) as a source and modulator of reactive oxygen species (ROS). Both functional loss of CII as well as its pharmacological inhibition can lead to ROS generation in cells, with a relevant impact ...
Kraus, Michal   +3 more
core   +1 more source

Galantamine-loaded PLGA nanoparticles reduce oxidative stress and inflammation in a rat model of spinal cord injury

open access: yesScientific Reports
Spinal cord injury (SCI) represents a debilitating condition with no effective treatments currently available. Previous research demonstrated that galantamine improves functional outcomes in SCI models. However, systemic administration results in limited
Fernanda Stapenhorst Franca   +7 more
doaj   +1 more source

Antimicrobial Actions of Reactive Oxygen Species

open access: yesmBio, 2011
Everything should be as simple as it can be, but not simpler.—Attributed to Albert Einstein (1) IMPORTANCE Reactive oxygen species (ROS) are produced by host phagocytes and exert antimicrobial actions against a broad range of pathogens.
Ferric C. Fang
doaj   +1 more source

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