Results 61 to 70 of about 862,038 (305)

CD40 ligand inhibits endothelial cell migration by increasing production of endothelial reactive oxygen species [PDF]

, 2002
Background— The CD40/CD40 ligand system is involved in atherogenesis. Activated T lymphocytes and platelets, which express high amounts of CD40 ligand (CD40L) on their surface, contribute significantly to plaque instability with ensuing thrombus ...
Dimmeler, S, Aicher, A, Stefanie Dimmeler, Urbich, C, Carmen Urbich, Andreas M. Zeiher, Alexandra Aicher, Elisabeth Dernbach, Zeiher, AM, Dernbach, E   +9 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

BMAA increases reactive oxygen species. [PDF]

, 2023
IMR-32 cells were treated with increasing doses of BMAA over a period of 24 hours. Flourescence of dichlorofluorescein (DCF) dye was used to determine cellular accumulation of reactive oxygen species (ROS) (A).
Bryan Burton (14768907), Ellie Moore (14768919), Karly Marx (14768910), Kaylei Wilcox (14768916), Keith Osowski (14768922), Kate Collins (7193567), Jarron Rowe (14768928), Jordan Riley (14768925), Matthew Pawlus (14768931), Jordan Brooks (11151486), Abigail Renner (14768913)   +10 more
core   +1 more source

Reactive Oxygen Species and Male Fertility

Antioxidants, 2020
Human infertility affects ~15% of couples worldwide, and it is now recognized that in half of these cases, the causes of infertility can be traced to men [...]
Cristian O’Flaherty
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Assessing the protection elicited by virus-like particles expressing the RSV pre-fusion F and tandem repeated G proteins against RSV rA2 line19F infection in mice

Respiratory Research
Excessive pulmonary inflammation is the hallmark of respiratory syncytial virus (RSV) infection hindering efficacious RSV vaccine development. Yet, the vast majority of the experimental RSV vaccine studies use laboratory-adapted RSV strains that do not ...
Min-Ju Kim, Ki Back Chu, Su-Hwa Lee, Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Eun-Kyung Moon, Fu-Shi Quan   +7 more
doaj   +1 more source

Influenza A hemagglutinin virus-like particles confer protection against influenza B virus infection

Emerging Microbes and Infections
Influenza A hemagglutinin (HA), neuraminidase, and/or M2e-containing virus-like particles (VLPs) induce immune responses that contribute to protection against multiple influenza A virus subtypes.
Jie Mao, Ki Back Chu, Gi-Deok Eom, Keon-Woong Yoon, Su In Heo, Hae-Ji Kang, Sung Soo Kim, Fu-Shi Quan   +7 more
doaj   +1 more source

Reactive oxygen species and redox compartmentalization

Frontiers in Physiology, 2014
Reactive oxygen species (ROS) formation and signaling are of major importance and regulate a number of processes in physiological conditions. A disruption in redox status regulation, however, has been associated with numerous pathological conditions.
Nina eKaludercic, Soni eDeshwal, Fabio eDi Lisa, Fabio eDi Lisa   +3 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Serum reactive oxygen species and apoptosis markers in septic patients [PDF]

, 2020
Background: Oxidative stress is one of the pathophysiological processes that occur during sepsis. Reactive oxygen species (ROS) production causes lipid peroxidation and protein and DNA damage. ROS and DNA damage triggers apoptosis.
Isabel Burgos, Manuel Alonso, Chapela, Sebastián Pablo, Schiel, Amalia, Sebastián Pablo Chapela, Burgos, Hilda Isabel, Amalia Schiel, Stella, Carlos Alberto, Carlos Alberto Stella, Alonso, Manuel   +9 more
core   +1 more source