Results 131 to 140 of about 1,596,363 (414)

Reactive Oxygen Species-Related Nanoparticle Toxicity in the Biomedical Field

Nanoscale Research Letters, 2020
The unique physicochemical characteristics of nanoparticles have recently gained increasing attention in a diverse set of applications, particularly in the biomedical field.
Zhongjie Yu, Qi Li, Jing Wang, Yali Yu, Yin Wang, Qihui Zhou, Peifeng Li   +6 more
semanticscholar   +1 more source

Moving Forwards by Blocking Back-Flow: The Yin and Yang of MI Therapy. [PDF]

, 2016
Mitochondrial reactive oxygen species production has emerged as an important pathological mechanism in myocardial ischemia/reperfusion injury. Attempts at targeting reactive oxygen species by scavenging using antioxidants have, however, been clinically ...
Brookes, Paul S, Chouchani, Edward T, Krieg, Thomas, Murphy, Michael P, Pell, Victoria R   +4 more
core   +2 more sources

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Degradation of organic compounds and production of activated species in Dielectric Barrier Discharges and Glidarc reactors [PDF]

arXiv, 2008
Major sterilization mechanisms are related to atoms and radicals, charged parti-cles, excited molecules, ozone, and UV radiation. The ROS (Reactive Oxygen Species) are well known as evildoers. These species are easily created in ambient air and water and they live long enough to reach the cell and attack the organic matter. Test molecules conversion in
arxiv  

Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2 [PDF]

, 2014
The antiglycemic drug metformin, widely prescribed as first-line treatment of type II diabetes mellitus, has lifespan-extending properties. Precisely how this is achieved remains unclear.
Billen, Johan, Braeckman, Bart, De Haes, Wouter, Depuydt, Geert, Frooninckx, Lotte, Schoofs, Liliane, Smolders, Arne, Temmerman, Liesbet, Van Assche, Roel   +8 more
core   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source

Reactive oxygen species attenuation in vitrified warmed bovine embryos. [PDF]

Edição dos resumos da 37ª Annual Meeting of the Brazilian Embryo Technology ...
DINIZ, J. H., FEUCHARD, V. L. da S., OLIVEIRA, C. S., OLIVEIRA, L. Z., QUINTAO, C. C. R., SARAIVA, N. Z.   +5 more
core  

Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements

Biomolecules, 2019
Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous ROS production in normal cells is controlled by the appropriate regulation between the silver lining of low and high ROS concentration mediated effects ...
V. Aggarwal, H. Tuli, Ayşegül Varol, Falak Thakral, M. Yerer, K. Sak, M. Varol, Aklank Jain, Md. Asaduzzaman Khan, G. Sethi   +9 more
semanticscholar   +1 more source

Peroxisomal regulation of redox homeostasis and adipocyte metabolism [PDF]

, 2019
Peroxisomes are ubiquitous cellular organelles required for specific pathways of fatty acid oxidation and lipid synthesis, and until recently their functions in adipocytes have not been well appreciated.
Klein, Samuel, Liu, Jingjing, Lu, Wen, Shi, Bimin, Su, Xiong   +4 more
core   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source