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The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran+5 more
wiley +1 more source
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez+3 more
wiley +1 more source
Nonenzymatic cleavage of proteins by reactive oxygen species generated by dithiothreitol and iron.
Kyuran Kim+2 more
openalex +1 more source
Involvement of Reactive Oxygen Species in N-(4-Hydroxyphenyl)retinamide-Induced Apoptosis in Cervical Carcinoma Cells [PDF]
Nobuhiko Oridate+5 more
openalex +1 more source
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali+5 more
wiley +1 more source
Evidence for reactive oxygen species inducing mutations in mammalian cells.
Abraham W. Hsie+5 more
openalex +1 more source
Fyn and JAK2 Mediate Ras Activation by Reactive Oxygen Species [PDF]
Jun‐ichi Abe, Bradford C. Berk
openalex +1 more source
A Different Perspective on the Solid Lubrication Performance of Black Phosphorous: Friend or Foe?
Researchers investigate black phosphorous (BP) as a standalone solid lubricant coating through ball‐on‐disc linear‐reciprocating sliding experiments in dry conditions. Testing on different metals shows BP doesn't universally reduce friction and wear. However, it achieves 33% friction reduction on rougher iron surfaces and 23% wear reduction on aluminum.
Matteo Vezzelli+5 more
wiley +1 more source
Bitumen ageing – Impact of reactive oxygen species
Bitumen from crude oil refinery is an important construction material as the binding component for asphalt mixes in road construction. Due to its organic composition, it is susceptible to oxidation when being exposed to reactive oxygen species (ROS ...
Bernhard Hofko+4 more
doaj
Glomerular macrophages produce reactive oxygen species in experimental glomerulonephritis
Neil Boyce+2 more
openalex +1 more source