Results 11 to 20 of about 857,471 (304)

Advances in Toxoplasma gondii Vaccines: Current Strategies and Challenges for Vaccine Development

Vaccines, 2021
Toxoplasmosis, caused by the apicomplexan parasite Toxoplasma gondii, is one of the most damaging parasite-borne zoonotic diseases of global importance.
Ki-Back Chu, Fu-Shi Quan
doaj   +1 more source

Influenza Virus-like Particle (VLP) Vaccines Expressing the SARS-CoV-2 S Glycoprotein, S1, or S2 Domains

Vaccines, 2021
The ongoing severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic had brought disastrous consequences throughout the entire world. While several manufactured vaccines have been approved for emergency use, continuous efforts to generate ...
Ki-Back Chu, Hae-Ji Kang, Keon-Woong Yoon, Hae-Ahm Lee, Eun-Kyung Moon, Beom-Ku Han, Fu-Shi Quan   +6 more
doaj   +1 more source

Excessive reactive oxygen species induce transcription-dependent replication stress. [PDF]

, 2023
Elevated levels of reactive oxygen species (ROS) reduce replication fork velocity by causing dissociation of the TIMELESS-TIPIN complex from the replisome.
Boleslavska, Barbora, Menon, Shruti, Janscak, P., Andrs, Martin, Surendranath, Kalpana, Rao, Satyajeet, Oravetzova, Anna, Dobrovolna, J., Kanagaraj, R., Chappidi, Nagaraja, Nascakova, Zuzana, Stoy, H., Lopes, M.   +12 more
core   +1 more source

Sublingual Vaccination with Live Influenza Virus Induces Better Protection Than Oral Immunization in Mice

Life, 2022
Both sublingual (SL) and oral vaccine administration modalities are convenient, easy, and safe. Here, we have investigated the differences in vaccine efficacy that are induced by oral and sublingual immunization with live influenza virus (A/Hong Kong/1 ...
Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Hae-Ji Kang, Ki-Back Chu, Fu-Shi Quan   +5 more
doaj   +1 more source

Reactive oxygen species and organellar signaling [PDF]

Journal of Experimental Botany, 2021
Abstract The evolution of photosynthesis and its associated metabolic pathways has been crucial to the successful establishment of plants, but has also challenged plant cells in the form of production of reactive oxygen species (ROS).
Su Yin Phua, Barbara De Smet, Claire Remacle, Kai Xun Chan, Frank Van Breusegem   +4 more
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Recombinant Vaccinia Virus Expressing Plasmodium berghei Apical Membrane Antigen 1 or Microneme Protein Enhances Protection against P. berghei Infection in Mice

Tropical Medicine and Infectious Disease, 2022
Recombinant vaccinia viruses (rVV) are effective antigen delivery vectors and are researched widely as vaccine platforms against numerous diseases. Apical membrane antigen 1 (AMA1) is one of the candidate antigens for malaria vaccines but rising concerns
Min-Ju Kim, Ki-Back Chu, Su-Hwa Lee, Hae-Ji Kang, Keon-Woong Yoon, Md Atique Ahmed, Fu-Shi Quan   +6 more
doaj   +1 more source

Preliminary Trichinella spiralis Infection Ameliorates Subsequent RSV Infection-Induced Inflammatory Response

Cells, 2020
Respiratory syncytial virus (RSV) infection affects the lives of neonates throughout the globe, causing a high rate of mortality upon hospital admission. Yet, therapeutic options to deal with this pulmonary pathogen are currently limited.
Ki-Back Chu, Hae-Ahm Lee, Hae-Ji Kang, Eun-Kyung Moon, Fu-Shi Quan   +4 more
doaj   +1 more source

Aryl-hydrocarbon receptor binding and the incidence of type 2 diabetes: the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

Environmental Health, 2020
Background Persistent organic pollutants (POPs) may cause diabetes, in part through aryl hydrocarbon receptor (AhR) binding. Ensuing mitochondrial dysfunction is postulated to mediate this effect.
Bruce B. Duncan, Cristina D. Castilhos, Paula A. Bracco, Maria I. Schmidt, Sora Kang, Suyeol Im, Hong-Kyu Lee, Álvaro Vigo, Youngmi K. Pak   +8 more
doaj   +1 more source

Reactive Oxygen Species

, 2019
Reactive oxygen species (ROS) are small unstable, highly reactive molecules with a short half-life derived by reduction of molecular oxygen. Once generated, ROS influence signalling molecules, in part through post-translational oxidative modification of proteins, modulating cellular function.
Livia de Lucca Camargo, Rhian M. Touyz
openaire   +2 more sources

Protection Induced by Vaccination with Recombinant Baculovirus and Virus-like Particles Expressing Toxoplasma gondii Rhoptry Protein 18

Vaccines, 2022
Heterologous immunization is garnering attention as a promising strategy to improve vaccine efficacy. Vaccines based on recombinant baculovirus (rBV) and virus-like particle (VLP) are safe for use, but heterologous immunization studies incorporating ...
Keon-Woong Yoon, Ki-Back Chu, Hae-Ji Kang, Min-Ju Kim, Gi-Deok Eom, Jie Mao, Su-Hwa Lee, Md Atique Ahmed, Fu-Shi Quan   +8 more
doaj   +1 more source