Hypothesis : soluble Aβ oligomers in association with redox-active metal ions are the optimal generators of reactive oxygen species in Alzheimer's disease [PDF]
, 2010 Considerable evidence points to oxidative stress in the brain as an important event in the early stages of Alzheimer's disease (AD). The transition metal ions of Cu, Fe, and Zn are all enriched in the amyloid cores of senile plaques in AD.
Tabner, Brian J +5 more
core +1 more source
Reactive oxygen species and cellular oxygen sensing [PDF]
Free Radical Biology and Medicine, 2007 Many organisms activate adaptive transcriptional programs to help them cope with decreased oxygen (O(2)) levels, or hypoxia, in their environment. These responses are triggered by various O(2) sensing systems in bacteria, yeast and metazoans. In metazoans, the hypoxia inducible factors (HIFs) mediate the adaptive transcriptional response to hypoxia by ...
Timothy P, Cash +2 more
openaire +2 more sources
The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells [PDF]
, 2008 Activated mast cells are a major source of the eicosanoids PGD(2) and leukotriene C(4) (LTC(4)), which contribute to allergic responses. These eicosanoids are produced following the ERK1/2-dependent activation of cytosolic phospholipase A(2), thus ...
Hye Sun Kuehn +11 more
core +1 more source
Interplay of catalyst corrosion and homogeneous reactive oxygen species in electrochemical ozone production [PDF]
, 2023 Electrochemical ozone production (EOP), a six-electron water oxidation, offers potentially sustainable routes for value-added oxidations and disinfectants, but progress in this field is slowed by a dearth in understanding fundamental mechanisms and how ...
Andrew, Lindsay +7 more
core +1 more source
Sensitive determination of reactive oxygen species by chemiluminescence methods and their application to biological samples and health foods [PDF]
, 2008 Sensitive and selective methods, based on chemiluminescence reactions, were introduced for determination of reactive oxygen species (ROS) and their applications to biological samples and health foods.
和田, 光弘
core +1 more source
Reactive oxygen species and redox signaling in breast cancer [PDF]
, 2017 Breast cancer progression depends on host innate and adaptive immune responses. Despite the effect of immune system in tumor destruction, cancer cells may induce the immune cells to support tumor progression.
Silva, Mateus Batista [UNESP] +4 more
core +1 more source
Journal of Orthopaedic Surgery, 2016 Purpose To evaluate cellular activity in milled versus unmilled surface of the femoral head in 21 patients who underwent robot-assisted total hip arthroplasty (THA). Methods The femoral head of 21 consecutive patients who underwent robot-assisted THA for
Kee Hyung Rhyu +3 more
doaj +1 more source
Reactive oxygen species and Covid-19
JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2020 No ...
Dwi Nur Ahsani
doaj +1 more source
Plasma reactive oxygen species levels are correlated with severity of age-related hearing impairment in humans [PDF]
, 2014 To investigate the relationship between plasma reactive oxygen species (ROS) levels and severity of age-related hearing impairment in humans. We recruited 302 adult subjects aged 40-77 years with normal or symmetrical sensorineural hearing loss.
許權振 ;劉殿楨 ;楊偉勛 +1 more
core +1 more source
Arteriosclerosis, Thrombosis, and Vascular Biology, 2004 Platelets participate not only in thrombus formation but also in the regulation of vessel tone, the development of atherosclerosis, angiogenesis, and in neointima formation after vessel wall injury. It is not surprising, therefore, that the platelet activation cascade (including receptor-mediated tethering to the endothelium, rolling, firm
Florian, Krötz +2 more
openaire +2 more sources