Results 101 to 110 of about 712,690 (299)
Regulation of reactive oxygen species during plant immunity through phosphorylation and ubiquitination of RBOHD. [PDF]
, 2020 Production of reactive oxygen species (ROS) is critical for successful activation of immune responses against pathogen infection. The plant NADPH oxidase RBOHD is a primary player in ROS production during innate immunity. However, how RBOHD is negatively
Castro, Bardo +8 more
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Multiphase composition changes and reactive oxygen species formation during limonene oxidation in the new Cambridge Atmospheric Simulation Chamber (CASC) [PDF]
, 2017 open7openGallimore, Peter J.; Mahon, Brendan M.; Wragg, Francis P. H.; Fuller, Stephen J.; Giorio, Chiara; Kourtchev, Ivan; Kalberer, MarkusGallimore, Peter J.; Mahon, Brendan M.; Wragg, Francis P. H.; Fuller, Stephen J.; Giorio, Chiara; Kourtchev, Ivan;
core +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Edaravone, a Radical Scavenger, Inhibits Mitochondrial Permeability Transition Pore in Rat Brain
Journal of Pharmacological Sciences, 2007 Edaravone, a radical scavenger, prevents ischemia/reperfusion injury in the brain, but the detailed mechanism is not known. This study examines the effect of edaravone on mitochondrial permeability transition pore (PTP) in rat brain.
Yuko Takayasu +6 more
doaj +1 more source
Detecting hydroxyl radical with a new two-photon fluorescent probe in living cells [PDF]
, 2018 Reactive oxygen species (ROS) are known to be involved in the onset and development of multiple diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and diabetes among others. Generation of ROS is a phenomenon that results from
Benitez-Martin, Carlos +4 more
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Journal of Inflammation Research, 2022 Dao-Fang Ding,1,2,* Yan Xue,3,* Xi-Chen Wu,1,2,* Zhi-Heng Zhu,1,2 Jia-Ying Ding,1,2 Yong-Jia Song,1,2 Xiao-Ling Xu,4 Jian-Guang Xu1,2 1Center of Rehabilitation Medicine, Yueyang Hospital, Shanghai University of Traditional Chinese Medicine ...
Ding DF +7 more
doaj
Cu,Zn superoxide dismutase genes in Tribolium castaneum: evolution, molecular characterisation and gene expression during immune priming. [PDF]
, 2017 The production of reactive oxygen species (ROS) is a normal consequence of the aerobic cell metabolism. Despite their high and potentially detrimental reactivity with various biomolecules, the endogenous production of ROS is a vital part of physiological,
Bakiu, Rigers +5 more
core +2 more sources
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source