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Reactive Oxygen Species (ROS)-Based Nanomedicine

Chemical Reviews, 2019
Reactive oxygen species (ROS) play an essential role in regulating various physiological functions of living organisms. The intrinsic biochemical properties of ROS, which underlie the mechanisms necessary for the growth, fitness, or aging of living organisms, have been driving researchers to take full advantage of these active chemical species for ...
Bowen Yang, Yu Chen, Jianlin Shi
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Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

Nature Reviews Molecular Cell Biology, 2020
'Reactive oxygen species' (ROS) is an umbrella term for an array of derivatives of molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the different ROS leads to molecular damage, denoted as 'oxidative distress'. Here we focus on ROS at physiological levels and their central role in redox signalling via different ...
Helmut, Sies, Dean P, Jones
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Reactive oxygen species (ROS)

Journal of Materials Chemistry B, 2021
Reactive oxygen species (ROS) are generated in cellular metabolism and are essential for cellular signalling networks and physiological functions. However, the functions of ROS are 'double-edged swords' to living systems that have a fragile redox balance between ROS generation and elimination.
He, Zhonglei   +6 more
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Reactive Oxygen Species (ROS)-responsive Organic Nanotubes

Chemistry Letters, 2021
Abstract Facilely synthesized thioether amphiphiles can self-assemble into nanotubes in water. The nanotubes exhibit quick reactive oxygen species (ROS)-responsivity in H2O2 or against the ultraviolet-triggered ROS from the encapsulated corannulene. Oxidation of the thioether amphiphile disassembles the long nanotubes into short ones and
Wuxiao Ding, Naohiro Kameta, Ayako Oyane
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Photocontrolled endogenous reactive oxygen species (ROS) generation

Chemical Communications, 2019
A photocleavable small molecule for superoxide generation.
Ajay Kumar Sharma   +2 more
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Reactive Oxygen Species (ROS) and Reproduction

1994
The role of reactive oxygen species (ROS) in reproduction has long been the subject of investigation. As for other systems described in this book, there is compelling evidence for the involvement of ROS in physiology and pathology of both male and female reproductive systems. In this chapter, we will first briefly summarize informations linking ROS and
E, de Lamirande, C, Gagnon
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Nanomaterials and Reactive Oxygen Species (ROS)

2020
One fundamental mechanism widely described for nanotoxicity from nanomaterials involves oxidative damage due to generation of free radicals and other reactive oxygen species (ROSs). Indeed, the ability of nanoscale materials to facilitate the transfer of electrons, and thereby promote oxidative damage or in some instances provide antioxidant protection,
Tao Wen   +3 more
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Reactive Oxygen Species (ROS): Key Components in Cancer Therapies

Anti-Cancer Agents in Medicinal Chemistry, 2022
Abstract: Reactive Oxygen Species (ROS) refers to the highly reactive substances which contain oxygen radicals. Hypochlorous acid, peroxides, superoxide, singlet oxygen, alpha-oxygen, and hydroxyl radicals are the major examples of ROS. Generally, the reduction of oxygen (O2) in molecular form produces superoxide (•O2 −) anion. ROS are produced during
Biswa Mohan Sahoo   +3 more
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