Results 81 to 90 of about 712,690 (299)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. [PDF]

, 2012
The altered metabolism of cancer can render cells dependent on the availability of metabolic substrates for viability. Investigating the signaling mechanisms underlying cell death in cells dependent upon glucose for survival, we demonstrate that glucose ...
Graeber, Thomas G, Graham, Nicholas A, Kohli, Bitika, Komisopoulou, Evangelia, Lo, Roger S, Mellinghoff, Ingo K, Mischel, Paul S, Ribas, Antoni, Tahmasian, Martik, Teitell, Michael A, Vivanco, Igor, Wu, Hong, Zhu, Maggie   +12 more
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Oxidative Stress and Inflammation in Cancer

Antioxidants
Reactive oxygen species (ROS) are important signaling molecules, physiologically synthesized by oxygen metabolism [...]
Daniela Sorriento
doaj   +1 more source

Oxidative damage and antioxidative system in algae

Toxicology Reports, 2019
Reactive oxygen species (ROS) typically produce in algae and act as secondary messengers in numerous cellular processes. Under abiotic stresses, the balance between production and suppression of ROS disappears and causes increase of ROS.
Maryam Rezayian, Vahid Niknam, Hassan Ebrahimzadeh   +2 more
doaj   +1 more source

Evidence for the impact of Reactive oxygen species on the control of branching in Neurospora crassa [PDF]

, 2011
In preliminary screens, several functions, most notably, genes involved in the control of reactive oxygen species (ROS), were identified as playing a role in the process of growth rate compensation of branch density.
Watters, Michael, Yablonowski, Jacob, Zapata, Alex   +2 more
core   +1 more source

How plants sense low oxygen [PDF]

, 2012
The recent identification of the oxygen-sensing mechanism in plants is a breakthrough in plant physiology. The presence of a conserved N-terminal motif on some ethylene responsive factors (ERFs), targets the protein for post-translational modifications ...
Perata, Pierdomenico, Pucciariello, Chiara   +1 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Reactive oxygen species induced by water containing nano-bubbles and its role in the improvement of barley seed germination [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Liu, S, Makino, Y, Oshita, S   +3 more
core  

Mitochondrial [dys]function; culprit in pre-eclampsia? [PDF]

, 2016
Mitochondria are extensively identified for their bioenergetic capacities; however, recently these metabolic hubs are increasingly being appreciated as critical regulators of numerous cellular signalling systems.
Kenny, Louise C., McCarthy, Cathal M.
core   +2 more sources