Results 101 to 110 of about 14,226,728 (252)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Research on the Strategy of Photovoltaic Grid-connected Generation and Reactive Power Regulation

open access: yesKongzhi Yu Xinxi Jishu, 2013
It designed a photovoltaic (PV) grid-connected power conditioner system integrating grid-connected generation and reactive power regulation , in which the PV grid-connected inverter can provide active power for grid and output reactive power which the ...
ZHAO Xianggui   +3 more
doaj  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Feasibility Study of Flexible Systems for Reactive Power

open access: yes
This paper presents the results obtained from a study of flexible reactive power compensation systems up to 100 kvar. Although the issue of reactive power and solutions for its reduction are not new, each case and object needs separate examination.
Zaķis, Jānis   +3 more
core  

Active and reactive power control of a VSC-HVdc

open access: yes, 2008
Voltage source converter-based HVdc(VSC-HVdc) systems have the ability to rapidly control the transmitted active power, and also to independently exchange reactive power with transmissions systems.
Ghandhari, Mehrdad,   +2 more
core   +1 more source

Reactive Power Control Modes in Smart Inverters for Overvoltage Mitigation: Impacts on LVRT Performance—A Case Study in Gorontalo, Indonesia

open access: yesIEEE Access
The increasing penetration of photovoltaic (PV) power generation into distribution networks presents an overvoltage challenge during normal operations. Smart inverter reactive power control modes are promising solutions to address this challenge.
Muammar Zainuddin   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Fast Adaptive Reactive-Power Compensation Control for Renewable Power Plants Considering Dynamic Active-Power–Voltage Coupling

open access: yes
Renewable power plants connected to low-system-strength grids are increasingly dominated by inverter-based resources (IBRs). Their point of common coupling (PCC) voltage is therefore shaped not only by reactive-power support but also by active-power ...
Yuqi Ao   +6 more
core   +1 more source

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