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Reactive Sulfur Species in Human Diseases
Antioxidants and Redox Signaling, 2023 Significance: Reactive sulfur species (RSS) have been recently recognized as redox molecules no less important than reactive oxygen species or reactive nitrogen species. They possess regulatory and protective properties and are involved in various metabolic processes, thereby contributing to the maintenance of ...
Małgorzata Iciek +2 more
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Chemiluminescence Measurement of Reactive Sulfur and Nitrogen Species
Antioxidants and Redox Signaling, 2022Significance: Reactive sulfur and nitrogen species such as hydrogen sulfide (H 2 S) and nitric oxide (NO • ) are ubiquitous cellular signaling molecules that play central roles in physiology and ...
Alexander R Lippert
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The Path to Controlled Delivery of Reactive Sulfur Species
Accounts of Chemical Research, 2021Reactive sulfur species (RSS) play regulatory roles in many physiological and pathological processes. Since the discovery of hydrogen sulfide (H2S) as a nitric oxide (NO)-like signaling molecule, understanding the chemical biology of H2S and H2S-related RSS, such as hydropersulfides (RSSH) and polysulfides (H2Sn), has become a fast-growing research ...
Xiang Ni +3 more
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Regulation of redox signaling by reactive sulfur species
Journal of Clinical Biochemistry and Nutrition, 2021 Reactive sulfur species, such as cysteine persulfide, are produced endogenously at significant levels in cells and have rapidly emerged as common biomolecules. By virtue of improved analytical methods for detecting reactive persulfides, it has been demonstrated that these reactive molecules exhibit unique chemical properties and are present in various ...
Shingo Kasamatsu, Hideshi Ihara
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Hypothesis: the role of reactive sulfur species in oxidative stress
Free Radical Biology and Medicine, 2001Oxidative stress arises from an imbalance in the metabolism of redox-active species promoting the formation of oxidizing agents. At present, these species are thought to include reactive oxygen, reactive nitrogen, and reactive nitrogen oxygen species (ROS, RNS, and RNOS, respectively).
Gregory I Giles, Claus Jacob
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The biology of reactive sulfur species (RSS)
Plant Physiology and Biochemistry, 2012Sulfur is an essential and quantitatively important element for living organisms. Plants contain on average approximately 1 g S kg⁻¹ dry weight (for comparison plants contain approximately 15 g N kg⁻¹ dry weight). Sulfur is a constituent of many organic molecules, for example amino acids such as cysteine and methionine and the small tripeptide ...
Martin C H, Gruhlke, Alan J, Slusarenko
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Reactive sulfur and selenium species in the regulation of bone homeostasis
Free Radical Biology and Medicine, 2022Reactive oxygen species (ROS) are important modulators of physiological signaling and play important roles in bone tissue regulation. Both reactive sulfur species (RSS) and reactive selenium species (RSeS) are involved in ROS signaling, and recent work suggests RSS and RSeS involvement in the regulation of bone homeostasis. For example, RSS can promote
Annie K, Gilbert +3 more
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Are Reactive Sulfur Species the New Reactive Oxygen Species?
Antioxidants & Redox Signaling, 2020Significance: Oxidative stress in moderation positively affects homeostasis through signaling, while in excess it is associated with adverse health outcomes. Both activities are generally attributed to reactive oxygen species (ROS); hydrogen peroxide as the signal, and cysteines on regulatory proteins as the target.
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Fluorescence Probes for Reactive Sulfur Species in Agricultural Chemistry
Journal of Agricultural and Food Chemistry, 2021Sulfur is an element that is indispensable throughout the growth of plants. In plant cells, reactive sulfur species (RSS) play a vital role in maintaining cellular redox homeostasis and signal transduction. There is demand accordingly for a simple, highly selective, and sensitive method of RSS detection and imaging for monitoring dynamic changes and ...
Xiaoyan Zeng +4 more
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Hydrogen sulfide, reactive sulfur species and coping with reactive oxygen species
Free Radical Biology and Medicine, 2019Life began in a ferruginous (anoxic and Fe2+ dominated) world around 3.8 billion years ago (bya). Hydrogen sulfide (H2S) and other sulfur molecules from hydrothermal vents and other fissures provided many key necessities for life's origin including catalytic platforms (primordial enzymes) that also served as primitive boundaries (cell walls ...
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