Results 181 to 190 of about 5,067,634 (225)

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source

Highlighted mechanistic aspects in the chemical biology of reactive sulfur species. [PDF]

Br J Pharmacol, 2019
Nagy P, Schwarz G, Kopriva S.
europepmc   +1 more source

Mesoporous PU/PEDOT:PSS Electrodes Reveal Population‐Level Stochastic Bioelectrical Dynamics in Marine Diatoms

Advanced Science, EarlyView.
Mesoporous mixed ionic‐electronic PU/PEDOT: PSS electrodes enable label‐free detection of stochastic extracellular bioelectrical dynamics in living Phaeodactylum tricornutum. Living diatoms actively modulate interfacial ionic dynamics, establishing stochastic electrochemical noise as a sensitive probe of microbial bioelectrochemical activity and a new ...
David M. S. Silva, Felipe L. Bacellar, Raquel Amaral, Louis‐Josselin Lavier‐Aydat, Luísa Cortes, Kamal Asadi, Leïla Tirichine, Paulo R. F. Rocha   +7 more
wiley   +1 more source

Small molecule generators of biologically reactive sulfur species. [PDF]

RSC Adv, 2018
Bora P, Chauhan P, Pardeshi KA, Chakrapani H.   +3 more
europepmc   +1 more source

Electrocatalytic C─C Bond Formation Via Cyanide Interception of CO2 Reduction Intermediates

Advanced Science, EarlyView.
ABSTRACT Electrochemical CO2 reduction offers a sustainable route to convert greenhouse gas into high‐value‐added chemicals, yet product distributions remain largely limited to simple C1‐C3 molecules. Here, we report a new reaction in which CO2 reduction intermediates undergo direct C‐C coupling with an external carbon nucleophile under electrochemical
Gongbo Liu, Liuru Fang, Dayu Zhu, Aimin Li, Haoming Yu, Chunlu Ding, Yuen‐Leong Chow, Mengjie Liu, Jianqi Geng, San H. Thang, Jie Zhang   +10 more
wiley   +1 more source

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol‐Mediated Cellular Uptake for miRNA Nano‐Drugs

Advanced Science, EarlyView.
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang, Hui Wang, Hao Zhang, Zhenkuan Cao, Zehui Liu, Siying Li, Hongda Wang, Yuping Shan   +7 more
wiley   +1 more source

Geminal-dithiol-based precursors for reactive sulfur species.

Chem Commun (Camb)
Xu S, Ramush G, Yang IJ, Das E, Shieh M, Xian M.   +5 more
europepmc   +1 more source

The ABCB7-Like Transporter PexA in Rhodobacter capsulatus Is Involved in the Translocation of Reactive Sulfur Species. [PDF]

Front Microbiol, 2019
Riedel S, Siemiatkowska B, Watanabe M, Müller CS, Schünemann V, Hoefgen R, Leimkühler S.   +6 more
europepmc   +1 more source

Effective Solvent‐Engineered All‐Inorganic CsPbI2Br Perovskite Solar Cells

Advanced Science, EarlyView.
All‐inorganic CsPbI2Br perovskite composition has gathered a lot of attention in recent years due to its thermal robustness, convenience for space applications as well as for the all‐perovskite triple junction applications as a top cell due to its wide‐bandgap (1.9 eV) nature.
Rajarshi Roy, Mahdi Malekshahi Byranvand, Tim Kodalle, Maximilian Krappel, Laxman Gouda, Stephan Boehringer, Chittaranjan Das, Mayank Kedia, Carolin M. Sutter‐Fella, Michael Saliba   +9 more
wiley   +1 more source

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source