Results 91 to 100 of about 844,980 (316)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Ca–Ag compounds in ethylene epoxidation reaction
Science and Technology of Advanced Materials, 2019 The ethylene epoxidation is a challenging catalytic process, and development of active and selective catalyst requires profound understanding of its chemical behaviour under reaction conditions.
Iryna Antonyshyn +8 more
doaj +1 more source
Mokslas: Lietuvos Ateitis, 2016 Aggregate alkaline corrosion of cement in concrete is going to respond in sodium and potassium hydroxide (lye) with active SiO2 found in some aggregates.
Aurimas Rutkauskas, Giedrius Girskas
doaj +1 more source
Cross-reactivity and tolerability of cephalosporins in patients with cell-mediated allergy to penicillins. [PDF]
, 2014 BACKGROUND AND OBJECTIVE: 13-Lactams are the most commonly used antibiotics but they can cause hypersensitivity reactions. We sought to estimate cross-reactivity and tolerability of cephalosporins in patients with cell-mediated allergy to penicillins ...
Colagiovanni, Amira +8 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2013 A computational approach using density functional theory to compute the energies of the possible σ-complex reaction intermediates, the “σ-complex approach”, has been shown to be very useful in predicting regioselectivity, in electrophilic as well as ...
Magnus Liljenberg +3 more
doaj +1 more source
Hyperarousal and sleep reactivity in insomnia: current insights [PDF]
, 2018 David A Kalmbach,1 Andrea S Cuamatzi-Castelan,1 Christine V Tonnu,1 Kieulinh Michelle Tran,1 Jason R Anderson,2 Thomas Roth,1 Christopher L Drake1 1Thomas Roth Sleep Disorders and Research Center, Henry Ford Health System, Detroit, MI, USA; 2Department ...
Drake CL +6 more
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
ChemistrySince ancient times, humans have turned to medicinal plants for treating various ailments and curing specific diseases, as these natural plants serve as the primary source of a range of phytochemicals, including triterpenes.
Yosra Trabelsi +3 more
doaj +1 more source
Atmosphere, 2019 Isoprene has a potentially large effect on ozone (O3) formation in the subtropical, highly polluted city of Guangzhou. Online measurements of isoprene in Guangzhou city are scarce; thus, isoprene levels were monitored for one year at the Guangzhou Panyu ...
Yu Zou +4 more
doaj +1 more source