Results 91 to 100 of about 1,806,003 (362)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The contribution of caregiver psychosocial factors to distress associated with behavioural and psychological symptoms in dementia [PDF]

, 2016
Copyright © 2016 John Wiley & Sons, Ltd. Objective: The objective of the study is to examine caregiver factors as predictors of BPSD-related distress and their potential mechanisms.
Ablitt, American Psychiatric Association, Ankri, Arbuckle, Bandeira, Baron, Bentler, Bentler, Bird, Campbell, Chan, Cheng, Craig, Crellin, Cummings, Cummings, EuroQoL Group, Fauth, Franche, Gaugler, Gonyea, Greene, Holmbeck, IBM Corp., Iecovich, Jackson, Jarrett, Kline, Kline, Knight, Lee, Lenior, Lyonette, Melo, Miranda-Castillo, Ngai, Orgeta, Ornstein, Pearlin, Powers, Preacher, Quinn, Reisberg, Roach, Schreiber, Siegert, Sobel, Springate, Spruyette, Steadman, Steiger, Tan, Teri, Townsend, Vernooij-Dassen, Vernooij-Dassen, Vugt, Wells, Williamson, Zarit   +59 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Ca–Ag compounds in ethylene epoxidation reaction

Science and Technology of Advanced Materials, 2019
The ethylene epoxidation is a challenging catalytic process, and development of active and selective catalyst requires profound understanding of its chemical behaviour under reaction conditions.
Iryna Antonyshyn, Olga Sichevych, Alim Ormeci, Ulrich Burkhardt, Karsten Rasim, Sven Titlbach, Marc Armbrüster, Stephan A. Schunk, Yuri Grin   +8 more
doaj   +1 more source

Lithuanian quarry aggregates concrete effects of alkaline corrosion tests / Lietuvos karjerų užpildų poveikio betono šarminei korozijai tyrimai

Mokslas: Lietuvos Ateitis, 2016
Aggregate alkaline corrosion of cement in concrete is going to respond in sodium and potassium hydroxide (lye) with active SiO2 found in some aggregates.
Aurimas Rutkauskas, Giedrius Girskas
doaj   +1 more source

The surface reactivity of iron oxide nanoparticles as a potential hazard for aquatic environments: A study on Daphnia magna adults and embryos [PDF]

, 2018
open5noNano-ecotoxicology is extensively debated and nanomaterial surface reactivity is an emerging topic. Iron oxide nanoparticles are widely applied, with organic or inorganic coatings for stabilizing their suspensions.

core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Advances in Research on Semi-Synthesis, Biotransformation and Biological Activities of Novel Derivatives from Maslinic Acid

Chemistry
Since ancient times, humans have turned to medicinal plants for treating various ailments and curing specific diseases, as these natural plants serve as the primary source of a range of phytochemicals, including triterpenes.
Yosra Trabelsi, Mansour Znati, Hichem Ben Jannet, Jalloul Bouajila   +3 more
doaj   +1 more source

Utilizing the σ-complex stability for quantifying reactivity in nucleophilic substitution of aromatic fluorides

Beilstein Journal of Organic Chemistry, 2013
A computational approach using density functional theory to compute the energies of the possible σ-complex reaction intermediates, the “σ-complex approach”, has been shown to be very useful in predicting regioselectivity, in electrophilic as well as ...
Magnus Liljenberg, Tore Brinck, Tobias Rein, Mats Svensson   +3 more
doaj   +1 more source

Evaluation of biodegradation kinetic constants for aromatic compounds by means of aerobic batch experiments [PDF]

, 2006
Kinetics of aerobic biodegradation have been investigated for twenty aromatic species using sludges collected from the aeration basin of municipal sewage treatment plants. The reproducibility of the results is tested with respect to the sludges period of
ANDREOZZI, ROBERTO, CESARO, RAFFAELE, MAROTTA, RAFFAELE, PIROZZI, FRANCESCO   +3 more
core   +1 more source