Results 191 to 200 of about 2,835,706 (332)

Manipulating Terminal Iron-Hydroxide Nucleophilicity through Redox. [PDF]

J Am Chem Soc
Oh J, Carsch KM, Zheng SL, Betley TA.
europepmc   +1 more source

Synthesis and Reactivity of Propargylamines in Organic Chemistry.

Chemical Reviews, 2017
Kate Lauder, A. Toscani, Nicolò Scalacci, D. Castagnolo   +3 more
semanticscholar   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Inclisiran in Dyslipidemia with High Residual Platelet Reactivity. [PDF]

Diseases
Kapsultanova D, Zhangelova S, Nurmukhammad F, Makasheva Z, Sakhov O, Galkina T, Rustamova F, Akhmentayeva D, Aubakirova B.   +8 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Specificity Evaluation of a Polyprotein-Based ELISA Designed for the Detection of Paratuberculosis in Multiple Species. [PDF]

Vet Med Int
Moyano RD, Colombatti Olivieri MA, Basconez González M, Garrido JM, Juste RA, Alonso MN.   +5 more
europepmc   +1 more source

Clopidogrel for Coronary Stenting Response Variability, Drug Resistance, and the Effect of Pretreatment Platelet Reactivity

Circulation, 2003
P. Gurbel, K. Bliden, B. L. Hiatt, C. O'connor   +3 more
semanticscholar   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Associations between attentional disengagement from distressed infant faces and cortisol reactivity are moderated by depressive symptoms in pregnant women: an eye-tracking study. [PDF]

Arch Womens Ment Health
Dworschak C, Paganini G, Beech A, Gunther KE, Rutherford HJV, Joormann J, Gadassi-Polack R.   +6 more
europepmc   +1 more source