Results 81 to 90 of about 662,342 (249)

High Cell Density Cultivation of HEK293 Cells Using a 2L Membrane‐Stirred Bioreactor

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The use of perfusion systems for the continuous cultivation of animal cells at high cell density (HCD) for the production of recombinant proteins, viruses, and viral vectors has many advantages. Besides an enhancement of volumetric productivity and high cell viability, the product quality can be improved through a steady‐state environment ...
Lennart Jacobtorweihe   +5 more
wiley   +1 more source

Dimensioness method of assessing the conditions of thermal shock to the reactor vessel [PDF]

open access: yesЯдерна фізика та енергетика, 2014
During the prolongation of the terms of the nuclear power plants operation the main issue is the substantiation of the possibility of the terms of the reactor vessel operation, which determines the economic necessity to con-tinue operating the unit as a ...
V. I. Skalozubov   +3 more
doaj  

Reactor vessel

open access: yes, 1999
A reactor vessel (1) comprises a reactor body (2) through which channels (3) are provided whose surface comprises longitudinal inwardly directed parts (4) and is provided with a catalyst (6), as well as buffer bodies (8, 12) connected to the channels (3)
Moulijn, J.A. (author)   +5 more
core   +1 more source

Intensification of Ester Production in a Continuous Reactor [PDF]

open access: yes, 2009
Numerous continuous intensified reactors are now accessible on the market that offer enhanced thermal performances in a continuous reactor. Such reactors are then particularly suited to fast and highly exothermic reactions.
Elgue, Sébastien   +6 more
core  

Jet injection studies for partially baffled mixing reactors: a general correlation for the jet trajectory and jet penetration depth [PDF]

open access: yes, 2008
This paper is devoted to the analysis of the jet trajectories, obtained using computational fluid dynamics (CFD), at two different scales (laboratory and industrial) with application to quenching of runaway reactions. One of the goals was to describe how
Fletcher, David F.   +5 more
core   +1 more source

Model‐Driven Monitoring and Parameter‐Based Development of an Escherichia coli Fed‐Batch Process for Production of a Fab Antibody Fragment Across Scales

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Maintaining consistent cellular physiology during bioprocess scale‐up or scale‐down is key to developing robust processes. However, the reliability of scale‐down bioreactor systems remains debated. Although the calibration of physiological parameters in mechanistic models across scales has been proposed as a scale‐down strategy, few studies ...
Fabian Schröder‐Kleeberg   +8 more
wiley   +1 more source

Gamma noise to non-invasively monitor nuclear research reactors

open access: yesScientific Reports
Autonomous nuclear reactor monitoring is a key aspect of the International Atomic Energy Agency’s strategy to ensure nonproliferation treaty compliance.
Oskari Pakari   +4 more
doaj   +1 more source

Use of the thermo-hydraulic system code RELAP5/MOD3.2 to transient analysis events of the VR-1 reactor

open access: yesActa Polytechnica
The article explores the application of the RELAP5 thermo-hydraulic code for transient simulations on the VR-1 research reactor, focusing on reactor vessel nodalisation and coolant stratification above the core.
Jakub Mátl, Filip Fejt
doaj   +1 more source

Proceedings of the OECD workshop on ex-vessel debris coolability

open access: yes, 2000
An OECD workshop on the safety of nuclear reactors, considering ex-vessel debris coolability, was organised in Karlsruhe, Germany, from 15 to 18 November 1999, in collaboration with Forschungszentrum Karlsruhe GmbH.
Alsmeyer, H. (ed.)   +2 more
core  

A General Workflow for Tangential Flow Filtration Perfusion Scale‐Up

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Tangential flow filtration (TFF) perfusion using hollow‐fiber modules offers substantial advantages over other mammalian cell retention technologies. Recently, increased awareness of Starling flow has helped to enhance filtration performance to similar, or even higher levels compared to alternative technologies.
Patrick Romann   +20 more
wiley   +1 more source

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