Results 91 to 100 of about 1,362,026 (232)

Safety in use of glucosylated steviol glycosides as a food additive in different food categories [PDF]

, 2018
The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion on the safety of glucosylated steviol glycosides proposed for use as a new food additive in different food categories.
Agneta Oskarsson, Alicja Mortensen, Ana Maria Rincon, Birgit Dusemund, Camilla Smeraldi, Claude Lambré, David Gott, Fernando Aguilar, Gunter Georg Kuhnle, Ine Waalkens‐Berendsen, Inger Therese Lillegaard, Ivan Stankovic, Jean‐Charles Leblanc, Maged Younes, Maria Jose Frutos, Matthew Wright, Metka Filipič, null null, Paul Tobback, Peter Aggett, Peter Moldeus, Pierre Galtier, Riccardo Crebelli, Rudolf Antonius Woutersen, Ursula Gundert‐Remy   +24 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Lessons Learned from Read-Across Case Studies for Repeated-Dose Toxicity [PDF]

A series of case studies designed to further acceptance of read-across predictions, especially for chronic health-related endpoints, have been evaluated with regard to the knowledge and insight they provide.
Cronin, MTD, Schultz, TW
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Building Your Library Strategically [PDF]

, 2003
Seven principles of library development should enable readers to build effective collections while wasting minimal amounts of time, money, and shelf space. (1) Plan to spend money. (2) Resolve that bigger is not necessarily better.
Smith, Gregory A
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Named persons in the Supreme Court: the Christian Institute and Others v The Lord Advocate [PDF]

, 2017
No abstract ...
McCarthy, Frankie, McCorkindale, Chris
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

The round-robin approach applied to nanoinformatics: consensus prediction of nanomaterials zeta potential

Beilstein Journal of Nanotechnology
A key step in building regulatory acceptance of alternative or non-animal test methods has long been the use of interlaboratory comparisons or round-robins (RRs), in which a common test material and standard operating procedure is provided to all ...
Dimitra-Danai Varsou, Arkaprava Banerjee, Joyita Roy, Kunal Roy, Giannis Savvas, Haralambos Sarimveis, Ewelina Wyrzykowska, Mateusz Balicki, Tomasz Puzyn, Georgia Melagraki, Iseult Lynch, Antreas Afantitis   +11 more
doaj   +1 more source

Words with wings [PDF]

, 2013
Speech presented at the Royal Commonwealth Society’s Essay Competition Awards Evening, 19 November ...
Kimber, Gerri
core