Results 81 to 90 of about 10,603,142 (281)

A virtual roundtable on Iser’s legacy Part I: conversation with Gerald Prince

Enthymema, 2017
In this article you find the first part of a roundtable on Wolfgang’s Iser legacy with Gerald Prince, Mark Freeman, Marco Caracciolo and Federico Bertoni. In Part I we discuss with Prof.
Gerald Prince, Laura Lucia Rossi
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Empathy translation in traditional Chinese medicine: Reader reception and paradigm building through the English translations of Shang Han Lun

New Techno-Humanities
This study investigates the emotional and cognitive reception of Shang Han Lun translations among global readers and explores how translation strategies can be optimized to enhance affective resonance and cultural intelligibility.
Tong Zhou, Jinghui Wang
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Syntax of Shadows  of the Unwritten Text in Postmodern Narratives.

مجلة اداب ذي قار
Using three main theoretical frameworks, this essay investigates the postmodern literature's instability of meaning and diversity of interpretation: Deconstruction, Intertextuality, and Reader-Response Theory.
Jameel Ibrahim Hassen
doaj   +1 more source

Euthanasia and Reincarnation: A Reader - Response Reading of Poe’s “The Tell- Tale Heart” [PDF]

Transcultural Journal of Humanities and Social Sciences
This paper sheds light on the reader as a crucial side of the triangle which includes: the reader, the text, and the author. Firstly, I highlight the contours of the reader – response theory by the prominent theorist Wolfgang Iser who stresses the role ...
Faten Dahy
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The Common Historian: on the Praxis of Reading the Past in Virginia Woolf’s The Common Reader

Études Britanniques Contemporaines
The past as Virginia Woolf presents it in The Common Reader is always a plural scene, inhabited by the present. Monuments like the tower of Caister Castle have jackdaws nesting in their walls, while Sophocles’ Greek city can be fashioned by the mind from
Olivier Hercend
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