Results 51 to 60 of about 6,049,564 (332)
A weak-constraint 4DEnsembleVar. Part I: formulation and simple model experiments
Tellus: Series A, Dynamic Meteorology and Oceanography, 2017 4DEnsembleVar is a hybrid data assimilation method which purpose is not only to use ensemble flow-dependent covariance information in a variational setting, but to altogether avoid the computation of tangent linear and adjoint models.
Javier Amezcua +2 more
doaj +1 more source
Hemifacial spasm in a patient with basilar artery dolichoectasia caused by uncontrolled hypertension [PDF]
Journal of Community Hospital Internal Medicine Perspectives, 2016 A 47-year-old male presented with a 2-year history of hemifacial spasm. Magnetic resonance imaging performed showed his tortuous basilar artery with nerve compression, and the patient was treated conservatively with botulinum toxin injections with ...
Gordon S. Crabtree +2 more
doaj +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Weight Loss and Self-Monitoring among Young Men in a Technology-Driven Weight Loss Intervention [PDF]
, 2019 Background Young men with obesity have double the mortality risk compared to young men with a healthy weight, but are notoriously challenging to recruit for behavioral weight loss (BWL) programs.
LaRose, Jessica G, Reading, Jean M
core +1 more source
Cognitive flexibility predicts early reading skills [PDF]
, 2014 International audienceAn important aspect of learning to read is efficiency in accessing different kinds of linguistic information (orthographic, phonological, and semantic) about written words.
Anderson +66 more
core +7 more sources
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
An affine almost positive roots model
, 2019 We generalize the almost positive roots model for cluster algebras from finite type to a uniform finite/affine type model. We define the almost positive Schur roots $\Phi_c$ and a compatibility degree, given by a formula that is new even in finite type ...
Reading, Nathan, Stella, Salvatore
core +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
HeliyonGeochemical tracers such as stable isotopes are widely used in groundwater studies for determining aquifer connectivity and groundwater-surface water interactions.
Jim Stanley, Lucy Reading
doaj +1 more source
Noncrossing partitions, clusters and the Coxeter plane [PDF]
, 2010 When W is a finite Coxeter group of classical type (A, B, or D), noncrossing partitions associated to W and compatibility of almost positive roots in the associated root system are known to be modeled by certain planar diagrams. We show how the classical-
Reading, Nathan
core +1 more source