Results 111 to 120 of about 964,538 (304)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The Potential of Children's Rearing Environment to Overcome Genetic Propensity for Low Reading Achievement. [PDF]

open access: yesMind Brain Educ, 2022
Leve LD   +6 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

The Evolving Relationship Between Reading Motivation and Achievement: A Longitudinal Study

open access: yesEducation Sciences
This study examined the reciprocal relationship between reading engagement or motivation and reading achievement across primary and secondary grades in Chile. Using longitudinal SIMCE data from a cohort of 47,073 students assessed in Grade 4 (ages 9–10),
Montserrat Cubillos, Rodrigo Troncoso
doaj   +1 more source

How Important are School Principals in the Production of Student Achievement? [PDF]

open access: yes
As school leaders, principals can influence student achievement in a number of ways, such as: hiring and firing teachers, monitoring instruction, and maintaining student discipline, among others. We measure the effect of individual principals on gains in
Dhuey, Elizabeth, Smith, Justin
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

The relationship of readiness factors to Jan. first grade reading achievement [PDF]

open access: yes, 1959
Thesis (Ed.M.)--Boston ...
Allen, Ruth J.   +8 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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