Results 81 to 90 of about 2,069,613 (288)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

School of self-education reading as a mean of training teacher for professional activities

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2019
At the Derzhavin Tambov State University, on the basis of which the regional branch of the Russian Reading Association was opened (the head of the local branch is Doctor of Sociology, professor of Derzhavin Tambov State University N.A.
G. M. Pervova G.M.
doaj   +1 more source

A FOUCAULDIAN READING OF DAVE EGGERS'S THE CIRCLE

open access: yesModernism and Postmodernism Studies Network, 2020
Post-Modernism has begun after modernism. In the post-modern period, the post-structuralists have been interested in many fields such as sociology, anthropology, and linguistics, etc. Michel Foucault, who is one of the French post-structuralists, published his Discipline and Punish: The Birth of the Prison in 1975.
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

EFFECTIVENESS OF LITERATURE CIRCLES ON STUDENTS’ READING COMPREHENSION

open access: yesIJOLTL: Indonesian Journal of Language Teaching and Linguistics, 2016
This study reports an experimental study to see the effect of literatures circles to improve reading comprehension of English department students of  State Islamic Institute (IAIN) of Samarinda. A quasi experimental research using nonrandomized control group pretest-posttest design was conducted to see effectiveness of literature circles on students ...
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A corpus-based study of cultural content in integrated course 1–4 New Advanced College English (3rd Edition)

open access: yesCogent Education
In the context of globalization, English textbook must balance local relevance and international perspectives to cultivate learners’ multicultural awareness.
Yuchen Xie, Chengming Gao, Yongzhi Liu
doaj   +1 more source

Reading Circles: Triggers for Increased Engagement of EFL Learners in Extensive Reading

open access: yesTeaching English as a Second or Foreign Language--TESL-EJ, 2023
While reading circles have been utilized to promote extensive reading in many educational settings, studies on higher levels of reading engagement in under-researched, English-as-a-foreign-language contexts are still in their infancy. Therefore, the current study examines the factors that increase learners’ levels of engagement in extensive reading ...
openaire   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

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