Results 51 to 60 of about 204,003 (345)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Fingerspelling as a Novel Gateway into Reading Fluency in Deaf Bilinguals. [PDF]

PLoS ONE, 2015
Studies have shown that American Sign Language (ASL) fluency has a positive impact on deaf individuals' English reading, but the cognitive and cross-linguistic mechanisms permitting the mapping of a visual-manual language onto a sound-based language have
Adam Stone, Adam Stone, Geo Kartheiser, Peter C Hauser, Laura-Ann Petitto, Thomas E Allen   +5 more
doaj   +1 more source

What predicts word reading in Arabic?

Frontiers in Psychology, 2023
Efficient and accurate word reading ability is critical for later reading success. As such, it is important to understand the component skills that underlie strong word reading ability.
Elsayed E. A. Hassanein, Evelyn S. Johnson, Sayed Ibrahim, Yousef Alshaboul   +3 more
doaj   +1 more source

Making Reading Fun: Using Reader’s Theater to Increase Interest, Fluency, and Comprehension in Reluctant Readers [PDF]

, 2011
Students with reading difficulties don\u27t enjoy reading, especially aloud in front of others. What can improve their interest in reading? Based on current trends demonstrating best practice, the use of Readers Theater may spark this interest for ...
Conrad, Raimie, McIver, Tiffanie, Miller, Ashley, Tino, Gabriella   +3 more
core   +1 more source

Visual motor skills and reading fluency: a correlational study [PDF]

, 2016
According to Van Hoorn, reading and writing skills involve adequate performance in visual–motor coordination, motor planning, cognitive and perceptual skills, and accurate processing of tactile and kinesthetic information. Scientific instruments aimed at
Altavilla, Gaetano, Di Tore, Pio Alfredo, Gervilli, Maria Grazia, Lipoma, Mario, Pignato, Salvatore, Raiola, Gaetano   +5 more
core   +1 more source

Reading Together: A Successful Reading Fluency Intervention

Literacy Research and Instruction, 2014
The article describes a reading fluency intervention called Reading Together that combines the method of repeated readings (Samuels, 1979) and the Neurological Impress Method (Heckelman, 1969). Sixteen volunteers from various backgrounds were recruited and trained to deliver the Reading Together intervention to struggling readers in third through fifth
Young, Chase, Mohr, Kathleen A. J., Rasinkski, Timothy   +2 more
openaire   +4 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Rapid Naming: The Importance of Different Reading and Spelling Dimensions

Avances en Psicología Latinoamericana, 2017
This research extends the empirical evidence regarding the influence of rapid naming on the acquisition of reading and spelling of European Portuguese in third and fourth grade children. In reading, it addresses different dimensions (accuracy and fluency)
Cristina P. Albuquerque
doaj   +1 more source

Assisted Reading with Digital Audiobooks for Students with Reading Disabilities [PDF]

, 2011
The goal of this study was to compare the efficacy of assisted reading with digital audiobooks with the traditional practice of sustained silent reading (SSR) in terms of reading fluency and reading attitude with upper elementary students with reading ...
Esteves, Kelli J., Whitten, Elizabeth
core   +2 more sources

READING FLUENCY THROUGH READER’S THEATER.

Ciencia Digital, 2018
El inglés es el idioma oficial de la ciencia y la tecnología. La mayor parte de la información publicada en el internet está escrita en este idioma, por esa razón para ser considerado un  profesional competente se debe aprender inglés desde los niveles iniciales de formación para desarrollar destrezas que permitan acceder a información actualizada. Con
Ana Jazmina Vera de la Torre, Elsa Mayorie Chimbo Cáceres, Wilma Elizabeth Suárez Mosquera, Verónica Elizabeth Masabanda Manotoa   +3 more
openaire   +2 more sources