Results 91 to 100 of about 777,557 (336)

Academic Libraries and Extracurricular Reading Promotion

open access: yesReference & User Services Quarterly, 2007
It is clear to anyone in the library profession, and certainly to readers of this column, that readers' advisory (RA) services have become an important part of libraries. While librarians have worked to connect readers and books throughout the history of libraries, the past eighteen years since the publication of Joyce Saricks's Readers' Advisory ...
Julie Elliott, Barry Trott
openaire   +3 more sources

Silicon utopias: the making of a tech startuo ecosystem in Manchester (UK) [PDF]

open access: yes, 2017
‘Silicon utopias’, the hope for a green, affluent and happy future through the creation of new tech-businesses, are today informing many urban development processes globally.
Pfeilstetter, Richard
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Marketing library services to children and young people [PDF]

open access: yes, 2006
This paper discusses the future of Schools Library Services in the North West region of England based on a research project recently undertaken by the Centre for the Public Library and Information in Society at the University of Sheffield on behalf of ...
Train, B., Wilson, K.
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Big Data Analytics in Library Services With AI: Personalized Content Recommendations and Catalog Optimization

open access: yesIEEE Access
This paper presents an AI-driven framework designed to enhance user engagement and optimize catalog management in digital libraries. The framework integrates Variational Autoencoder (VAE)-based personalized recommendations with Adam optimizer and ...
Pinjia Hu, Yichi Zhang
doaj   +1 more source

Performance Analysis Comparison Of Coca Cola And Pepsi [PDF]

open access: yes, 2014
All companies fight to get as many consumers as they can and it makes, product, price, place and promotion become important factors to make a company has a successful marketing campaign. The companies spend much money for create an attractive product at
Saerang, D. P. (David)   +2 more
core  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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