Results 101 to 110 of about 5,254,799 (333)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Neural Speed Reading with Structural-Jump-LSTM

, 2019
Recurrent neural networks (RNNs) can model natural language by sequentially 'reading' input tokens and outputting a distributed representation of each token.
Alstrup, Stephen, Hansen, Casper, Hansen, Christian, Lioma, Christina, Simonsen, Jakob Grue   +4 more
core  

Eye movements and reading in glaucoma: observations on patients with advanced visual field loss [PDF]

, 2014
Purpose To investigate the relationship between reading speed and eye movements in patients with advanced glaucomatous visual field (VF) defects and age-similar visually healthy people.
A Pollatsek, AC Viswanathan, C Lamirel, David P. Crabb, DP Crabb, DP Crabb, EE Freeman, FC Glen, GS Rubin, GW McConkie, HJ Husband, JM White, K Fujita, K Rayner, M Ishii, MA Bullimore, MD Crossland, MD Crossland, ND Smith, ND Smith, Nicholas D. Smith, P Ramulu, PA Aspinall, PY Ramulu, PY Ramulu, PY Ramulu, R Asaoka, R Burton, R Flesch, R Susanna Jr, Robyn Burton, S Kutlay, S Martin-Chang, T Nicholson, U Altangerel, WG Thorpe   +35 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Speed of Reading Instructions for Creative Task Performance: Influence of Typography and Reading Media

Applied Sciences
Teachers often serve as creators of written instructions that students use to complete assignments. This research investigates whether the speed at which the instructions are read is impacted by different visual designs (such as typeface shape, colour ...
Marija Toure, Helena Gabrijelčič Tomc, Klementina Možina   +2 more
doaj   +1 more source

Reading performance in children with visual function anomalies [PDF]

, 2014
Aims - To compare reading performance in children with and without visual function anomalies and identify the influence of abnormal visual function and other variables in reading ability.
Lança, Carla Costa, Prista, João, Serra, Helena   +2 more
core   +1 more source

Effects of visual span on reading speed and parafoveal processing in eye movements during sentence reading.

Journal of Vision, 2014
The visual span (or ‘‘uncrowded window’’), which limits the sensory information on each fixation, has been shown to determine reading speed in tasks involving rapid serial visual presentation of single words.
Sarah Risse
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Neurovisual training (TRIGRAM) in young patients with visual-perceptive dyslexia [PDF]

, 2017
Dyslexia is a language-based learning disability. Although this condition is characterized by anatomical malformation of the brain, it seems that the typical reading pattern of dyslexic may be also related to more complex sensory deficits.
CARLESIMO, Sandra Cinzia, Marchegiani, Chiara, MIGLIORINI, Raffaele, PACELLA, Elena, PACELLA, FERNANDA, SEGNALINI, Alessandro, TURCHETTI, PAOLO   +6 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source