Results 81 to 90 of about 158,391 (248)

Velocidad de lectura e inteligencia en estudiantes de ingeniería

open access: yesRevista de Psicología, 2018
En esta investigación se tuvo por objetivo determinar la relación entre la inteligencia y la velocidad de lectura. Para ello se tomó una muestra de 175 estudiantes universitarios del primer semestre de dos carreras de Ingeniería en una universidad ...
Walter Lizandro Arias Gallegos   +1 more
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Psychometric analysis of the revised CompLEC test to measure reading speed and reading comprehension in university students. [PDF]

open access: yesBMC Psychol, 2023
Alburqueque CMA   +6 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Yetişkin Bireylerde Yaş, Eğitim ve Cinsiyet Değişkenlerinin Okuma Hızına Etkisi

open access: yesDil, Konuşma ve Yutma Araştırmaları Dergisi, 2018
Giriş: Oldukça karmaşık bir işlem olan okuma; “yazılı sembolleri tanımak ve bunları anlayarak yorumlamak” şeklinde tanımlanmakta ve görme, anımsama ve anlamlandırma olmak üzere üç aşamadan oluşmaktadır (Talmaç, 2013). Okuma akıcılığı, temel olarak, okuma
Eda İyigün   +2 more
doaj  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The Effect of Speed Reading Technique on Second-Grade Students’ Reading Comprehension Levels

open access: yesSAGE Open
This study aims to examine the effect of speed reading techniques on second-grade students’ reading speed and reading comprehension levels. In today’s information age, improving reading skills is vital for academic and professional success. The study was
Yasin Özkara   +2 more
doaj   +1 more source

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