Results 91 to 100 of about 4,221,594 (325)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Effect of magnification and field of view on reading speed using a CCTV

open access: yes, 1987
Reading speeds were measured in 18 subjects with normal vision and 10 with low vision for each of 20 experimental conditions with different magnifications and field sizes on the Closed Circuit Television System (CCTV). There was a significant difference
Lovie-Kitchin, Jan E.   +4 more
core   +1 more source

Improving Reading Speed and Biology Conceptual Understanding using Speed Reading Method on Students of X-MIA SMA

open access: yesJurnal Pendidikan Sains, 2018
: Speed reading method helps students to learn effectively, efficiently, and independently in understanding a reading. This study aims to improve the reading speed and understanding of students’ biology concepts by applying speed reading method.
Edi Sulistiyono   +2 more
doaj   +1 more source

Are e-books effective tools for learning? Reading speed and comprehension: iPad® vs. paper

open access: yes, 2015
Recently, electronic books (e-books) have become prevalent amongst the general population, as well as students, owing to their advantages over traditional books.
Suzanne Sackstein   +2 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Simulating Speed in Language: Contributions from vision, audition and action

open access: yes, 2015
Embodied theories propose that understanding meaning in language requires the mental simulation of entities being referred to. These mental simulations would make use of the same modality-specific systems involved in perceiving and acting upon such ...
Speed, LJ
core  

THE READING COMPREHENSION: A CLINICAL AND QUANTITATIVE EVALUATION

open access: yesRa Ximhai, 2016
The main theme of this research is the reading comprehension, arises and valued a proposal for intervention in a primary school. The participants were both second grade parallel groups, called control and experimental, to this last one, strategies are ...
Efrén Viramontes-Anaya   +2 more
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Speed reading for beginners : panduan membaca lebih cepat, lebih cerdas, dan dengan pemahaman yang lebih baik

open access: yes, 2012
Informasi meledak di mana-mana. Ia muncul lewat buku, media massa, gadget, juga internet. Semua orang dituntut bisa memahami informasi engan cepat. Kalau tidak, informasi lewat begitu saja atau akhirnya menenggelamkan kita.
Muhammad Noer
core  

Reading Speed and Reading Comprehension in an English-Medium Instruction Context.

open access: yes
The undeniable importance of reading in higher education prompted this investigation into the reading skills of a group often overlooked in previous research: master’s level students studying in English-medium instruction (EMI) environments. Participants
Shaw, Philip,   +3 more
core   +1 more source

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