Results 111 to 120 of about 1,251,984 (298)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

The impact of the text and background color on the screen reading experience

open access: yesTehnički Glasnik, 2017
Everyday use of modern technologies implies the need for an optimization of readability and legibility parameters used for the reading of text on screen.
Anja Zorko   +4 more
doaj  

Efficacy of Cognitive-Motor Rehabilitation on the Reading Speed and Cognitive Flexibility of Children with Learning Disabilities in Reading [PDF]

open access: yesپژوهش‌های کاربردی روانشناختی
The objective of the current study was to investigate the efficacy of cognitive-motor rehabilitation in improving the reading speed and cognitive flexibility of children with disability during the reading learning process.
Mozhgan Soltani   +3 more
doaj   +1 more source

Teaching high frequency words to poor readers using flashcards : its effects on novel word acquisition, skill trasfer to in-text word reading, and passage reading competencies : a thesis in partial fulfillment of the requirements for the degree of Master of Educational Psychology, Massey University, Albany, New Zealand [PDF]

open access: yes, 2016
Several literacy reports published in the last decade have emphasised the large gap in the reading attainment of children in New Zealand. A common barrier that prevents poor readers to catch up to their peers is difficulty in reading fluency, which is ...
Iqbal, Butul Samera
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

ドウキヅケトリュウチョウナヨミノカンレンニツイテ 10プンタドクニオケルブンセキ [PDF]

open access: yes, 2016
  The present study is a practical research about 10-minute extensive reading-the participants read graded readers for their level for ten minutes. The purpose of the study is two fold.
城野 博志
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

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