Results 161 to 170 of about 4,221,594 (325)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Increasing Reading Speed: Timed versus Repeated-timed Reading
, 2016 This confirmatory quantitative pilot study investigated the effect of timed-reading (TR), and comparative treatments of timed-reading versus repeated-timed-reading (RR) on 18 female 2nd-year university students of English as a foreign language.
3190, Leroux, Todd
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Reading on small displays: reading performance and perceived ease of reading
The present thesis explores and discusses reading continuous text on small screens, namely on mobile devices, and aims at identifying a model capturing those factors that most influence the perceived experience of reading.
Tikka, Piiastiina
core
Software for Improving Reading Speed [PDF]
, 2018 Käesoleva magistritöö eesmärk oli uurida olemasolevat tarkvara lugemiskiiruse arendamiseks ning luua veebipõhine kiirlugemise õppimise rakendus. Rakendus pakub erinevat liiki kiirlugemisharjutusi ja teksti mõistmist kontrollivaid küsimusi.
Siiber, Marten
core
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Extensive reading as a breakthrough in a traditional EFL curriculum: experimental research in junior high schools in Taiwan [PDF]
The main focus of this research was to examine the effects of extensive reading on junior high school students' language proficiency and learning attitude development, compared with those who received the current reading IR (grammar/translation-based ...
Sheu, Ping-Huang
core
Contrast sensitivity and binocular reading speed best correlating with near distance vision-related quality of life in bilateral nAMD. [PDF]
Ophthalmic Physiol Opt, 2020 Rossouw P, Guichard MM, Hatz K.
europepmc +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source