Results 151 to 160 of about 4,221,594 (325)

Multimodal Evaluation of Visual Function in Geographic Atrophy versus Normal Eyes

Clinical Ophthalmology, 2020
Noemi Burguera-Giménez,1– 3 Santiago García-Lázaro,2 Enrique España-Gregori,4,5 Roberto Gallego-Pinazo,6 Neus Burguera-Giménez,2 Manuel Rodríguez-Vallejo,3 Gowtham Jonna1 1Ophthalmology Department, Retina ...
Burguera-Giménez N, García-Lázaro S, España-Gregori E, Gallego-Pinazo R, Burguera-Giménez N, Rodríguez-Vallejo M, Jonna G   +6 more
doaj  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

The Contribution of RAN Pause Time and Articulation Time to Reading Across Languages: Evidence From a More Representative Sample of Children

, 2015
We examined the relationship between rapid automatized naming (RAN) components – articulation time and pause time – and reading fluency across languages varying in orthographic consistency. Three hundred forty-seven Grade 4 children (82 Chinesespeaking
Parrila, Rauno, Georgiou, George K., Aro, Mikko, Liao, Chen-Huei   +3 more
core   +1 more source

Binocular Reading Speed Comparison: Patients After Bilateral Trifocal IOL Implantation versus Those without Cataract —A Prospective, Dual-Center Study

Clinical Ophthalmology
Yingjie Lin,1– 3 Xianjun Liang,1,2 Yongchang Tan,1 Yun Chen,1 Li Li,1 Yanxue Xu,1,3 Chunyang Zhao,1 Haokun Qu2 1Department of Ophthalmology, Aier Eye Hospital, Jinan University, Guangzhou, Guangdong, People’s Republic of China; 2Department of ...
Lin Y, Liang X, Tan Y, Chen Y, Li L, Xu Y, Zhao C, Qu H   +7 more
doaj  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Text Formatting Effects in Speed Reading

, 1980
Text page-layout may influence both reading speed and comprehension. Available data obtained from low-speed readers suggests a superiority for two-column format over full-page format. As reading speed increases, visual scanning strategies change.
James L. Knight, Anita V. Kak
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The Effects of Reading Speed and Retrieval Practice on Reading Comprehension

, 2019
Undergraduate Honors ...
Weimer, Carrie A.
core