Results 111 to 120 of about 337,644 (263)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Strategies for Reading

open access: yes, 2006
Contents Part 1. Introduction 1. What is reading? 2. How do we read? 3. Schema theory. 4. Efficient and inefficient reading 5. Re-conceptualizing education and reading 6. Reading and culture (s) and culture (s) of reading 7. Importance of classroom talk and discussion in the reading classroom. 8. Testing reading 9. The text and the reader 10.
openaire   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

The Correlation between Reading Strategies and Reading Achievement Across Learning Styles

open access: yesIndonesian EFL Journal: Journal of ELT, Linguistics, and Literature, 2018
The study was aimed to analyze the interrelationship between metacognitive reading strategy and reading achievements, the correlation between cognitive reading strategy and reading achievement, and to know the effect between metacognitive and cognitive ...
Syaiful Islam
doaj  

Reading Strategies of Multilingual ESL Learners across Culturally Familiar and Unfamiliar Texts in Eswatini

open access: yesJournal of English Language Teaching Fakultas Pendidikan Bahasa dan Seni Program Studi Pendidikan Bahasa Inggris IKIP Mataram
Reading comprehension in multilingual contexts requires more than linguistic competence; it demands metacognitive regulation and strategic flexibility across culturally diverse materials.
Mfanukhona Wonderboy Kunene   +1 more
doaj   +1 more source

Cortical tracking of speech in noise accounts for reading strategies in children. [PDF]

open access: yesPLoS Biol, 2020
Destoky F   +10 more
europepmc   +1 more source

Reading Comprehension Strategies

open access: yes8TH INTERNATIONAL VISIBLE CONFERENCE ON EDUCATIONAL SCIENCE AND APPLIED LINGUISTICS Book of Proceedings, 2017
The academic success of the university students greatly depends on the mastery of an academic reading skill. However, students as well as teachers, take the learning of this skill for granted, as they tend to presuppose that reading skill is acquired as a part of their secondary education.
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

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