Results 81 to 90 of about 8,224,631 (288)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Investigating Metacognitive Strategies for overcoming Barriers to Reading Comprehension: Insights from a Pakistani Context

Journal of Language and Cultural Education, 2018
The main aim of this research was to investigate metacognitive strategies through reading comprehension practice by first year students of engineering departments.
Channa Mansoor Ahmed, Abassi Abdul Malik, Nordin Zaimuariffudin Shukri, Muhammad Jam Khan, Arain Rubina Shaheen   +4 more
doaj   +1 more source

READING STRATEGIES IN EFL CLASSROOM: A THEORETICAL REVIEW

Cendekia: Jurnal Pendidikan dan Pembelajaran, 2014
Teaching reading has been long discussed in the context of English teaching curriculum in Indonesia.  The ground of English curriculum (e.g. 1984, 1994, 2004 English curriculum) lays reading as the main model of teaching English in the secondary school ...
Teguh Budiharso
doaj   +1 more source

The Effectiveness of a Metacognitive Strategy during the Reading Process on Cognitive Allocation and Subject Matter Retention

, 2022
Peng Lu, Savannah Schroeder, Scott Burris, John Rayfield, Matt Baker   +4 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Male and female Indonesian EFL undergraduate students’ metacognitive strategies in academic reading: planning, monitoring and evaluation strategies

, 2021
Erina Andriani, Concilianus Laos Mbato
openalex   +2 more sources

Developing Argumentation Skills through Reading Strategies in the 8th and 9th Grades [PDF]

, 2022
Luiza Bizhanova, Aigul Koishigarina, Gulzada Pussurmanova, Aigul Yensepova   +3 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The Effect of Using RAP Strategy on Developing Reading Comprehension Skills for Seventh Graders in Gaza Governorates

, 2021
Mohammed Mousa Nahhal
openalex   +2 more sources

Metacognitive Reading Strategies, Motivation, and Reading Comprehension Performance of Saudi EFL Students

, 2016
Metacognitive reading strategies and reading motivation play a significant role in enhancing reading comprehension. In an attempt to prove the foregoing claim in a context where there is no strong culture for reading, this study tries to find out if ...
Joel C. Meniado
semanticscholar   +1 more source