Results 81 to 90 of about 1,934,051 (281)
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Techniques to Conduct Research in Metacognition and Reading
During the last twenty years a great amount of research has been devoted to the area of metacognition and reading comprehension. Taking into account the importance of this type of research for people interested in the teaching and learning of reading ...
Jesús Alirio Bastidas
doaj
An Analysis On Classroom Technique On Reading Class For Facing National Examination At The Third Grade Of SMP N 1 Jatipurno In 2017/ 2018 Academic Year [PDF]
This research aimed at describing the techniques used by teacher, reading activity used in the classroom, and teacher’ roles on reading class for facing national examination at the third grade of SMP N 1 Jatipurno in 2017/ 2018 academic year. The type of
, Drs. Djoko Srijono, M.Hum +1 more
core
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
GERMAN VERBS IN STUDIO-D A1 BOOK: A MORPHOLOGY ANALYSIS [PDF]
The study aimed at describing: (1) the patterns of German verbs in Studio- D A1 book, and (2) the function of verbs in German sentences. The object of this study was a lingual unit in the form of German verbs taken from Studio- D A1 book.
Triyono, Sulis
core
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source

