Results 81 to 90 of about 559,455 (353)
FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
The form of sound through hybrid materials [PDF]
, 2016 The poster was presented at the SIGGRAPH '16 Special Interest Group on Computer Graphics and Interactive Techniques Conference, Anaheim, CA — July 24 - 28, 2016.
Ferrarello L. +3 more
core +1 more source
Molecular Oncology, Volume 19, Issue 8, Page 2412-2430, August 2025.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Advanced Engineering Research, 2011 The application technique of computer graphics for processing the experimental data in the mode of real time is presented. The data are received in the research practice of modern material science.
Victor N. Pustovoit +2 more
doaj
Real-Time Simulation of a Cerebellar Scaffold Model on Graphics Processing Units
Frontiers in Cellular Neuroscience, 2021 Large-scale simulation of detailed computational models of neuronal microcircuits plays a prominent role in reproducing and predicting the dynamics of the microcircuits. To reconstruct a microcircuit, one must choose neuron and synapse models, placements,
Rin Kuriyama +4 more
doaj +1 more source
Computer simulations and real-time control of ELT AO systems using graphical processing units [PDF]
SPIE Proceedings, 2012 The adaptive optics (AO) simulations at the Thirty Meter Telescope (TMT) have been carried out using the efficient, C based multi-threaded adaptive optics simulator (MAOS, http://github.com/lianqiw/maos). By porting time-critical parts of MAOS to graphical processing units (GPU) using NVIDIA CUDA technology, we achieved a 10 fold speed up for each GTX ...
Wang, Lianqi, Ellerbroek, Brent
openaire +4 more sources
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Perceptually optimized real-time computer graphics [PDF]
, 2012 Perceptual optimization, the application of human visual perception models to remove imperceptible components in a graphics system, has been proven effective in achieving significant computational speedup.
Smith, Jeffrey
core +1 more source
3D Weather – Towards a Real-time 3D Simulation of Localised Weather presented at EVA 2011 [PDF]
, 2011 Weather forecasts are nearly always portrayed from either a satellite view perspective, a numerical or symbol based representation. None of these methods actually portray weather visually from the point of view of the observer, that is, they do not ...
Head, A
core +1 more source