Results 71 to 80 of about 17,888,844 (245)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Real-Time Monte Carlo Denoising With Adaptive Fusion Network
IEEE AccessReal-time Monte Carlo denoising aims to denoise a 1spp-rendered image with a limited time budget. Many latest techniques for real-time Monte Carlo denoising utilize temporal accumulation (TA) as a pre-processing to improve the temporal stability of ...
Junmin Lee +3 more
doaj +1 more source
Real-time Photorealistic Stereoscopic Rendering of Fire
, 2007 Fire. (Under the direction of Dr. David McAllister.) We propose a method for real-time photorealistic stereo rendering of the natural phenomenon of fire.
Benjamin Michael +6 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Real-Time Motion Blur Using Multi-Layer Motion Vectors
Applied SciencesTraditional methods for motion blur, often relying on a single layer, deviate from the correct colors. We propose a multilayer rendering method that closely approximates the motion blur effect.
Donghyun Lee, Hyeoksu Kwon, Kyoungsu Oh
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Fiblets for Real-Time Rendering of Massive Brain Tractograms
, 2022 We present a method to render massive brain tractograms in real time. Tractograms model the white matter architecture of the human brain using millions of 3D polylines (fibers), summing up to billions of segments.
Boubekeur, Tamy +3 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
High-fidelity rendering on shared computational resources [PDF]
The generation of high-fidelity imagery is a computationally expensive process and parallel computing has been traditionally employed to alleviate this cost.
Aggarwal, Vibhor
core