Results 81 to 90 of about 17,888,844 (245)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

There-reality : selective rendering in high fidelity virtual environments [PDF]

, 2007
There-reality environments are those virtual environments which evoke the same perceptual response from a viewer as if they were actually present, or there, in the real scene being depicted.
Paulo dos Santos, Luis, Chalmers, Alan, Mastoropoulou, Georgia, Debattista, Kurt, Santos, Luís Paulo   +4 more
core   +1 more source

A Real-time Service Oriented Infrastructure [PDF]

, 2010
The advancements in distributed computing have driven the emergence of service-based infrastructures that allow for on-demand provision of ICT assets. Taking into consideration the complexity of distributed environments, significant challenges exist in ...
Michael Boniface, Voith, T, Soren Berger, Cucinotta, T, Tommaso Cucinott, Dimosthenis Kyriazis, Voith, Thomas, Eduardo Oliveros, Oberle, K, Andreas Menychtas, Karsten Oberle, Kyriazis, D, Kyriazis, Dimosthenis, Menychtas, Andreas, Oliveros, Eduardo, Thomas Voith, Oberle, Karsten, Menychtas, A, Tommaso Cucinotta, Berger, Sören, George Kousiouris, Oliveros, E, Kousiouris, George, Berger, S, Boniface, Mike, Kousiouris, G, Cucinotta, Tommaso   +26 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Real-time map rendering and interaction: a stylized hierarchical symbol model

International Journal of Digital Earth
Digital maps, serving as pivotal instruments in the realm of geographic information services, adeptly encapsulate spatial data through refined graphics and symbols.
Kejia Huang, Di Liu, Taisheng Chen, Yiwen Wang, Chenliang Wang, Wenjiao Shi   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Real‐Time Mobile Transmission and Rendering of UAV LiDAR Massive Point Cloud

IET Radar, Sonar & Navigation
To address the limitations of existing UAV‐mounted LiDAR systems, this paper proposes an innovative real‐time transmission and rendering technology for massive point cloud data.
Yingjie Gao, Wenqi Wang, Ning Chen, Weilin Ren, Quanyi Ye   +4 more
doaj   +1 more source

Distributed OpenGL Rendering in Network Bandwidth Constrained Environments [PDF]

, 2011
Display walls made from multiple monitors are often used when very high resolution images are required. To utilise a display wall, rendering information must be sent to each computer that the monitors are connect to.
McGregor, Anthony James, Hunkin, Paul, Neal, Braden   +2 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source