Results 221 to 230 of about 1,220,561 (394)

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Sensitive detection and differentiation of rhinoviruses and enteroviruses by a nested real-time RT-PCR assay. [PDF]

Microbiol Spectr
Ogura M, Ohnishi T, Yaginuma M, Kobayashi H, Furuichi M, Inose R, Kato S, Shinjoh M.   +7 more
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Development and evaluation of a real-time RT-PCR assay for Mammarenavirus guanaritoense virus detection. [PDF]

BMC Infect Dis
Dolgova AS, Gladkikh AS, Polev DE, D'Angelo P, Alarcón V, García N, Arias Y, Monsalve I, Rodriguez L, Shabalina AV, Chayeb VA, Sukhikh IS, Briceño E, Dedkov VG.   +13 more
europepmc   +1 more source

Development, Evaluation, and Clinical Application of PRRSV-2 Vaccine-like Real-Time RT-PCR Assays. [PDF]

Viruses, 2023
Rawal G, Krueger KM, Yim-Im W, Li G, Gauger PC, Almeida MN, Aljets EK, Zhang J.   +7 more
europepmc   +1 more source

Advancing Broad Bean True Mosaic Virus Detection Using Rt-Pcr and Real-Time Rt-Pcr with Novel Primer Set Design

Fumino Nito, Hitoshi Oya, Takayuki Matsuura, Hironobu Yanagisawa   +3 more
openalex   +1 more source

Cyclin E Expression in Operable Breast Cancer Quantified Using Real-Time RT–PCR: A Comparative Study with Immunostaining [PDF]

, 2005
Piotr Potemski, Elżbieta Płuciennik, Andrzej K. Bednarek, Renata Kusińska, Dorota Jesionek‐Kupnicka, Grażyna Pasz‐Walczak, Cezary Watała, Radzisław Kordek   +7 more
openalex   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Development of a multiplex real-time RT-PCR assay for simultaneous detection of 18 respiratory viruses. [PDF]

Front Cell Infect Microbiol
Xu A, Xie L, Zhong L, Zhao X, Wan Z, Wang JH, Zhang C.   +6 more
europepmc   +1 more source

AML hastalarında t(15;17) PML-RARA translokasyonunun real time RT-PCR ile 5 yıllık sonuçlarının değerlendirilmesi

, 2014
Tezcanlı Kaymaz B, Vildan Bozok Çetintaş, Tetik Vardarlı A, Yılmaz üslüer S, Duygu Aygüneş, Ayşegül Dalmızrak, Çağdaş Aktan, Ali Şahin Küçükaslan, Tuğçe B. Balcı, Çağla Kayabaşı, Özmen Yelken B, Selvi Günel N, Biray Avcı Ç, Buket Kosova, Zühal Eroğlu, Serap Aksoylar, Nazan Çetingül, Can Balkan, Deniz Yılmaz, Yeşim Aydınok, K Avaklı, Mahmut Töbü, Murat Tombuloğlu, Fatma İrem Şahin, Filiz Büyükkeçeci, Gülsevim Saydam, Cumhur Gündüz   +26 more
openalex   +2 more sources