Results 161 to 170 of about 1,878,090 (267)

Cardiovascular pharmacotherapy and real-world data [PDF]

European Heart Journal - Cardiovascular Pharmacotherapy, 2018
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Effectiveness and safety of mirikizumab in ulcerative colitis: real-world data from the Latium Net. [PDF]

BMJ Open Gastroenterol
Murgiano M, Balestrieri P, Calabrese E, Fiorino G, Festa S, Pugliese D, Di Vincenzo F, Puca P, Parello S, Vespasiano V, Colella A, Marafini I, Profeta F, Foscarini E, Papa A, Lopetuso LR, Monteleone G, Cicala M, Gasbarrini A, Laterza L, Scaldaferri F.   +20 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Real-World Data on the Use of Follitropin Delta in a Dutch IVF Center. [PDF]

Reprod Med Biol
Boom P, Creutzberg EC, Koster MPH, Laven JSE.   +3 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Primary extragonadal germ cell tumours: Real-world data from a high-volume centre. [PDF]

BJUI Compass
Kidess M, Hentrich M, Aschl F, Chernova O, Beckstein S, Bojko P, Schulz S, Neitz J, Hermans J, Volz Y, Ebner B, Keller P, Apfelbeck M, Marcon J, Weinhold P, Stief CG, Eismann L, Chaloupka M.   +17 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Lecanemab and amyloid-related imaging abnormalities: Real-world data from a single center experience. [PDF]

Alzheimers Dement (Amst)
Wallace A, Zhou O, Hoang MN, Porter G, Padilla C, Marshall C.   +5 more
europepmc   +1 more source

[Real world data].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2018
Kashif Waqar, Faiz, Espen Saxhaug, Kristoffersen   +1 more
openaire   +1 more source