Results 141 to 150 of about 3,045,873 (317)
Real-World Data as Real Evidence Showing Real-World Outcomes
Journal of Kidney CancerN ...
openaire +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Little Green Data Book 2009
, 2009 The 2009 edition of the little green data book includes a focus section, four introductory pages that focus on a specific issue related to development and the environment. This year the focus is on urban areas and
World Bank
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
International Journal of Public HealthObjectivesTo analyze the costs and medication patterns of patients with chronic kidney disease (CKD) and comorbidities in Xuzhou, China, using a large electronic medical records database.MethodsData were obtained from an electronic medical records ...
Wan Jie +23 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
, 2014 The Little Data Book 2014 is a pocket edition of World Development Indicators 2014. It is intended as a quick reference for users of the World Development Indicators database, book, and mobile app. The database covers more than 1,200 indicators and spans
World Bank
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 2013 The Little Data Book 2013 is a pocket edition of World Development Indicators 2013. It is intended as a quick reference for users of the World Development Indicators database, book, and mobile app.
World Bank
core +1 more source
Discover Health SystemsPurpose Real-world evidence (RWE) and real-world data (RWD) have become integral to regulatory, clinical, and policy decision-making. Yet oncology registries—the most structured and disease-specific RWD sources—remain fragmented, inconsistently governed,
Alexandros Sagkriotis
doaj +1 more source