Results 131 to 140 of about 3,045,873 (317)

The Little Green Data Book 2004

, 2004
The Little Green Data Book 2004 is based on the World Development Indicators 2004, and represents a succinct collection of information. It is a collaboration between the Development Economics Data Development Group,
World Bank
core   +1 more source

A Review of the Importance and Relevance of Real-World Data and Real-World Evidence

Medical Science Monitor
Real-world data are routinely collected data associated with patient health status or delivery of health care from sources including patient registries, electronic health records (EHRs), medical claims data, or digital health technologies. Real-world evidence is generated from specified clinical real-world data and includes evidence of the use ...
openaire   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

World Bank Group/World Bank Corporate Scorecards, April 2016

, 2016
This pamphlet presents the World Bank Group and World Bank Corporate Scorecards updated with latest data available for Tier 3 (Performance Tier) as of December 31, 2015. Tiers 1 and 2 present data from end of fiscal year 2015.
World Bank Group
core   +1 more source

Real-world study: from real-world data to real-world evidence [PDF]

Translational Breast Cancer Research, 2020
openaire   +1 more source

Inaccurate Real-World Data Does Not Provide Real-World Answers

American Journal of Therapeutics, 2021
Gabriela, Buffet, Raul, Mendoza-Sassi, Marinos, Fysekidis   +2 more
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The EU project Real4Reg: unlocking real-world data with AI [PDF]

Background The use of real-world data is established in post-authorization regulatory processes such as pharmacovigilance of drugs and medical devices, but is still frequently challenged in the pre-authorization phase of medicinal products.
Julia Wicherski, Peggy Maguire, Liisa Pylkkänen, Joana Fernandes, Rebecca Moore, McNamara, Hillary, Bräuner, Elvira, Kallio, Aleksi, Pylkkänen, Liisa, Kerstin Pfeifer, Martin Russek, de Valck, Dirk, Russek, Martin, Paakinaho, Anne, Peltner, Jonas, Monika Roberta Korcinska Handest, Vera Ehrenstein, Haenisch, Britta, Aleksi Kallio, Blair Rajamaki, Nagy, David, Sirpa Hartikainen, Tolppanen, Anna Maija, Cláudia Furtado, Hartikainen, Sirpa, Wicherski, Julia, Korcinska Handest, Anne Paakinaho, Fernandes, Joana, Christoph Röthlein, Hess, Steffen, Mohamed Aborageh, Aborageh, Mohamed, Pfeifer, Kerstin, Maguire, Peggy, Dávid Nagy, Roethlein, Christoph, Vanessa Moore, Dirk De Valck, Tolppanen, Anna-Maija, Lentzen, Manuel, Ehrenstein, Vera, Hillary McNamara, Moore, Vanessa, Evy Reviers, Manuel Lentzen, Jonas Peltner, Silva, Célia, Fröhlich, Holger, Anna-Maija Tolppanen, Hartikainen, Sirpa A., Froehlich, Holger, Korcinska Handest, Monika Roberta, Britta Haenisch, Reviers, Evy, Niels Henrik Meedom, Monika Roberta, Inês Costa, Silja Wortberg, Holger Fröhlich, Wortberg, Silja, Moore, Rebecca, Costa, Inês, Furtado, Cláudia, Becker, Cornelia, Pylkkänen, Liisa H., Elvira Bräuner, Horvath-Puho, Erzsebet, Thuan Vo, Cornelia Becker, Meedom, Niels Henrik, Steffen Heß, Célia Silva, Erzsébet Horváth-Puhó, Rajamaki, Blair, Vo, Thuan, Röthlein, Christoph   +76 more
core   +1 more source

Real-world treatment patterns and outcomes for patients with non-metastatic non-small cell lung cancer: retrospective analyses in Canada, England, and Germany

BMC Pulmonary Medicine
Background Recent therapeutic advancements for non-metastatic non-small cell lung cancer (NSCLC) have increased the need for real-world baselines against which future changes in patient management and clinical outcomes can be compared.
Alastair Greystoke, Melinda J. Daumont, Caroline Rault, Hannah Baltus, Philip Q. Ding, Gabrielle Emanuel, Stefano Lucherini, Lien Vo, Valeria M. Saglimbene, Eleanor Ralphs, Cátia Leal, Minouk J. Schoemaker, Alexander Katalinic, Annika Waldmann, Winson Y. Cheung   +14 more
doaj   +1 more source

Adopting a Societal Perspective in Health-Economic Evaluation: Analysis of Nine HTA Methodological Guidelines on How to Integrate Societal Costs

Journal of Market Access & Health Policy
Objective: The perspective applied in Health Technology Assessment (HTA) has recently been presented as a central methodological debate in HTA. Beyond expected effects on patients’ health and quality of life, health technologies can affect broader ...
Chloé Gervès-Pinquié, Hortense Nanoux, Sarah Akarkoub, Rémi Brazeilles, Henri Bonnabau, Katell Le Lay   +5 more
doaj   +1 more source